Concha Vázquez Martínez

Vázquez, José Manuel Bernardi López

doi:10.17075/adg.2008.22269

Cited by 1 publication

(1 citation statement)

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…For instance, in the vascular tissue engineering field as a vascular patch which act as a mechanical backbone for vascular tissue regeneration while providing anti-thrombogenic properties [10]. Besides, it also can be applied in skin tissue engineering for reducing the rigidity of scaffold and promoting angiogenesis [22]. The scaffold also can aid in strain absorption during bone mechanical loading while improving cell activity which attributes to bone tissue regeneration [4,23].…”

Section: Resultsmentioning

confidence: 99%

Morphology and Wettability Analyses on Electrospun Polyvinyl Alcohol/Elastin Nanofibers at Varying Voltages and Composition

Vangetaraman,

Asiri,

Sivalingam

et al. 2024

Advances in Science and Technology

View full text Add to dashboard Cite

Electrospinning technique is widely used to fabricate nanofibrous membranes mimicking the extracellular matrix structure. The utilization of synthetic polyvinyl alcohol (PVA) as the base material to construct electrospun nanofibers is often related to the limitation of biological function. Therefore, in this study, elastin (EL), a natural polymer, was incorporated into PVA matrix to overcome the biofunctional limitation. The ideal electrospinning parameters for the fabrication of PVA/EL electrospun nanofibers were investigated by varying the compositions of PVA/EL at 9.9/0.1, 9.5/0.5 and 9.0/1.0 (v/v) and the applied voltages at 18, 20 and 22 kV. With the increasing voltage from 18 to 22 kV, the mean fiber diameter decreased for the PVA and PVA/EL of 9.9/0.1 (v/v) while a fluctuating trend was observed for the 9.5/0.5 and 9.0/1.0 (v/v). The homogenous nanofibers construction with no beads was observed in the PVA/EL 9.5/0.5 (v/v). Both PVA and PVA/EL nanofibrous membranes displayed hydrophilicity with water contact angles below than 90°. In conclusion, the PVA/EL 9.5/0.5 (v/v) fabricated at 20 kV, possessed the ideal fiber morphology and wettability, to be subjected for biomedical applications.

show abstract