Concise review of mechanisms of bacterial adhesion to biomaterial surfaces

Abstract

This article reviews the mechanisms of bacterial adhesion to biomaterial surfaces and the factors affecting the adhesion. The process of bacterial adhesion includes an initial physicochemical interaction phase (phase one) and a late molecular and cellular interaction phase (phase two), which is a complicated process affected by many factors, including the characteristics of the bacteria themselves, the target material surface, and the environmental factors, such as the presence of serum proteins or bactericidal substances.

Tunable conjugated polymers for bacterial differentiation

“…Many factors affect bacterial adhesion to a surface, including the properties of the surface material, environmental conditions and also the bacterial cell surface properties, and this makes it a complex and multifactorial phenomenon [40,[54][55][56][57][58]. Bacterial cell attachment to a surface is generally described by two stages; initial attachment, which is rapid and reversible and involves physicochemical interactions between bacterial cell surfaces and the material surfaces, and non-reversible attachment, which involves specific and non-specific interactions between proteins on the bacterial surface structures and binding molecules on the material surface, as well as physicochemical interactions [59,60].…”

Medical biofilms

“…Biofilm formation continues with the transport of cells to the substratum:liquid interface, which is governed by a combination of transport mechanisms (i.e., diffusion, convection, sedimentation, and motility) (Bryers, 2000). Once at a substratum surface, bacterial cells adhere by non-specific and/or specific receptor:ligand adhesion mechanisms (An and Friedman, 1998;Busscher et al, 1992;Glantz et al, 1999). Within minutes of attachment, adherent cells up-regulate the secretion of certain cell signal molecules that orchestrate communitywide phenotypic responses, through a process termed quorum sensing (Bjarnsholt and Givskov, 2007;Camilli and Bassler, 2006;Davies et al, 1998;Harraghy et al, 2007;Hodgkinson et al, 2007;Horswill et al, 2007;Pritchard, 2006;Rumbaugh, 2007).…”

Investigation of Structural, Morphological, Magnetic Properties and Biomedical applications of Cu2+ Substituted Uncoated Cobalt Ferrite Nanoparticles

“…Non metal substituted magnetic nanoparticles are used in various biomedical applications because of its high Curie temperature, magneto crystalline-anisotropy and super paramagnetic behavior at room temperature [22] . The adhesion of substratum surface with bacterial cell is being governed by several factors such as physico-chemical properties of substratum, physico-chemical properties of bacterium and suitable environmental conditions in which the adhesion happens [23,24] . Beyond the above mentioned factors, the degree of adhesion of a given bacterium differs with surface properties of the synthesized transition metals substituted nanoparticles.…”