In the modern era, disruptive technologies, ranging from artificial intelligence to big data analytics and virtual reality to drone technology, have profoundly impacted India's lifestyles and employment dynamics. This chapter deeply explores these innovations' history, meaning, theory, and significance, focusing mainly on their transformative influence on the Indian industries, health, transport, and energy sectors. Beyond just an exploration, this study employs DEA for efficiency benchmarking, offering a structured assessment of how well these sectors have harnessed the potential of disruptive technologies. The analysis underscores the diverse issues, challenges, and opportunities arising from integrating these technologies and the subsequent shifts in employer-employee relationships and challenges posed to governance. Furthermore, the chapter elaborates on the real-world implementations of these technologies and their broader ramifications, including cost reductions, sustainability, and socially responsible practices in the concerned sectors.