Concomitant peripheral vascular and coronary artery disease: A new dimension for the global endovascular specialist?

Abstract

SummaryBackground: Early and accurate diagnosis of peripheral atherosclerosis is of paramount importance for global management of patients with known coronary artery disease (CAD).Hypothesis: We sought to evaluate retrospectively the prevalence and clinical relevance of significant abdominal vessel stenosis or aneurysm (AVA) in patients undergoing coronary angiography.Methods: Medical records of consecutive patients who underwent coronary angiography at two public institutions over a 12-month period were evaluated. Angiographic results of patients who underwent diagnostic abdominal aorta angiography, based on clinical criteria, to evaluate abdominal vessels at the same time as coronary angiography were analyzed.Results: During the study period, AVA was reported in 180 (35.7%) of 504 consecutive patients (335 men, mean age 68 ± 13.8 years): renal artery stenosis was found in 13.1% of cases (66 patients), aortoiliac artery disease in 13.7% (69 patients), and aortic aneurysmal disease in 8.9% (45 patients). Logistic regression analyses revealed ≥ 3-vessel CAD (odds ratio [OR] 9.917 , p = 0.002), age > 65 years (OR 3.817, p = 0.036), ≥ 3 risk factors (OR 2.8, p = 0.048) as independent predictors of AVA.Conclusion: Multiple vascular atherosclerotic distributions are frequent in elderly patients who have multivessel CAD and

The Prevalence and Quantification of Atherosclerosis in an Elderly Population Assessed by Whole-Body Magnetic Resonance Angiography

“…In the present study, relationships between the degrees of atherosclerosis in different territories were observed. Previously, atherosclerosis of the coronary arteries and of the vascular territories has been shown to be related, 19,20 a finding that together with our results emphasizes that atherosclerosis is a generalized disease.…”

A total atherosclerotic score for whole-body MRA and its relation to traditional cardiovascular risk factors

“…Coronary arteries are not included in the WBMRA examination, which means that a major contributor to CV events is not evaluated. Atherosclerosis is though a systemic disease, and if stenosis is present in one vascular region the likelihood is high that other vascular areas will be affected by significant asymptomatic disease [16,17]. In a previous study, an atherosclerosis index as revealed by WBMRA was related to coronary artery calcium [4].…”