A 68-year-old man with severe aortic stenosis (AS) and marked left ventricular hypertrophy (LVH), underwent aortic valve replacement (AVR). Preoperative echocardiography demonstrated contact between the anterior mitral leaflet and the interventricular septum during diastole without mitral regurgitation (MR), i.e., "pseudo systolic anterior motion (SAM)." After a mechanical prosthesis had been implanted, severe mitral regurgitation MR and pulmonary hypertension occurred due to "true" SAM of the mitral valve. Despite intensive management, it was difficult to control MR in the acute phase. In the chronic phase, echocardiography revealed the resolution of both SAM and MR. It is suggested that the dramatic reduction of afterload after alleviation of valvular stenosis by prosthetic replacement and increased flow velocity in the left ventricular outflow tract (LVOT) caused SAM with MR. The risk of SAM after AVR should be considered in AS patients with marked LVH, especially in the presence of "pseudo SAM." Keywords: aortic valve replacement, systolic anterior motion, mitral regurgitation, left ventricular hypertrophy
IntroductionIt has been reported that an abnormal systolic intraventricular flow velocity (AFV) can occur soon after aortic valve replacement (AVR) for aortic stenosis (AS) in patients with concentric left ventricular hypertrophy (LVH).1 Asymmetrical septal hypertrophy is not uncommon in patients with severe AS, and left ventricular outflow tract (LVOT) obstruction is often not prominent until valvular stenosis is alleviated by inserting a prosthesis.2 Here, we report a patient who underwent AVR for AS and developed systolic anterior motion (SAM) with mitral regurgitation (MR). Preoperative echocardiography demonstrated "pseudo SAM" without MR, but the patient then developed SAM during surgery together with acute pulmonary hypertension caused by severe MR, and required aggressive management to achieve hemodynamic stability. His MR was eventually controlled by medication without the need for additional surgery.
Case ReportA 68-year-old man was referred for surgical treatment of severe AS. On admission, echocardiography revealed severe calcific AS and prominent LVH with an interventricular septal thickness of 17 mm and a posterior wall thickness of 14 mm. The anterior leaflet and chordae of the mitral valve (MV) came into contact with the septum during diastole, but there was no MR. These findings were consistent with "pseudo SAM" A 68-year-old man with severe aortic stenosis (AS) and marked left ventricular hypertrophy (LVH), underwent aortic valve replacement (AVR). Preoperative echocardiography demonstrated contact between the anterior mitral leaflet and the interventricular septum during diastole without mitral regurgitation (MR), i.e., "pseudo systolic anterior motion (SAM)." After a mechanical prosthesis had been implanted, severe mitral regurgitation MR and pulmonary hypertension occurred due to "true" SAM of the mitral valve. Despite intensive management, it was difficult to control MR in the acute p...