Concordance between fMRI and Wada test for memory lateralization in temporal lobe epilepsy: A meta-analysis and systematic review

Massot‐Tarrús, Andreu; White, Kevin P.; Mousavi, Seyed Reza; Hayman-Abello, Susan; Hayman‐Abello, Brent; Mirsattari, Seyed M.

doi:10.1016/j.yebeh.2020.107065

Cited by 13 publications

(10 citation statements)

References 27 publications

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“…The present findings further indicate tfMRI predicts postsurgical cognitive outcomes following temporal lobe epilepsy surgery; however, results were significant only for patients with left TLE. This differential result agrees with reports demonstrating patients with left TLE have more negative postsurgical cognitive outcomes, 51 presumably because these patients receive intervention within the hemisphere that is likely dominant for language function 2–6 . As such, tfMRI may be more sensitive to postsurgical cognitive morbidity among this subgroup.…”

Section: Discussionsupporting

confidence: 88%

“…This differential result agrees with reports demonstrating patients with left TLE have more negative postsurgical cognitive outcomes, 51 presumably because these patients receive intervention within the hemisphere that is likely dominant for language function. [2][3][4][5][6] As such, tfMRI may be more sensitive to postsurgical cognitive morbidity among this subgroup. Among patients with left TLE, language tfMRI was shown to be more broadly predictive of postsurgical cognitive outcomes than memory tfMRI, although memory tfMRI was more sensitive to verbal memory outcomes than language tfMRI.…”

Section: Discussionmentioning

confidence: 99%

“…Cognitive domainEffect size outcomes within language and memory tfMRI studies of left TLE were further moderated by postsurgical cognitive domain (Q M[6] = 91.08, p < .0001).Memory tfMRI studies of verbal memory outcomes (Figure4A; k = 12, ̂ = −.37, SE = .10, Z = −3.…”

mentioning

confidence: 92%

“…Task-based functional magnetic resonance imaging (tfMRI) has developed as a common alternative in epilepsy surgery to the intracarotid amobarbital procedure (IAP), also known as the Wada procedure. 1,2 Multiple prior research syntheses have demonstrated diagnostic concordance between tfMRI and IAP, [2][3][4][5][6] implicating tfMRI as a comparable predictor of postsurgical cognitive outcomes. A review of the current literature conducted by the American Academy of Neurology Guideline Development, Dissemination, and Implementation Subcommittee assessed issues regarding the added value of tfMRI for the prediction of cognitive outcomes after anterior temporal lobectomy (ATL).…”

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confidence: 99%

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Task‐based functional magnetic resonance imaging prediction of postsurgical cognitive outcomes in temporal lobe epilepsy: A systematic review, meta‐analysis, and new data

et al. 2022

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Task‐based functional magnetic resonance imaging (tfMRI) has developed as a common alternative in epilepsy surgery to the intracarotid amobarbital procedure, also known as the Wada procedure. Prior studies have implicated tfMRI as a comparable predictor of postsurgical cognitive outcomes. However, the predictive validity of tfMRI has not been established. This preregistered systematic review and meta‐analysis (CRD42020183563) synthesizes the literature predicting postsurgical cognitive outcomes in temporal lobe epilepsy (TLE) using tfMRI. The PubMed and PsycINFO literature databases were queried for English‐language articles published between January 1, 2009 and December 31, 2020 associating tfMRI laterality indices or symmetry of task activation with outcomes in TLE. Their references were reviewed for additional relevant literature, and unpublished data from our center were incorporated. Nineteen studies were included in the meta‐analysis. tfMRI studies predicted postsurgical cognitive outcomes in left TLE (trueρ̂ = −.27, 95% confidence interval [CI] = −.32 to −.23) but not right TLE (trueρ̂ = −.02, 95% CI = −.08 to .03). Among studies of left TLE, language tfMRI studies were more robustly predictive of postsurgical cognitive outcomes (trueρ̂ = −.27, 95% CI = −.33 to −.20) than memory tfMRI studies (trueρ̂ = −.27, 95% CI = −.43 to −.11). Further moderation by cognitive outcome domain indicated language tfMRI predicted confrontation naming (trueρ̂ = −.32, 95% CI = −.41 to −.22) and verbal memory (trueρ̂ = −.26, 95% CI = −.35 to −.17) outcomes, whereas memory tfMRI forecasted only verbal memory outcomes (trueρ̂ = −.37, 95% CI = −.57 to −.18). Surgery type, birth sex, level of education, age at onset, disease duration, and hemispheric language dominance moderated study outcomes. Sensitivity analyses suggested the interval of postsurgical follow‐up, and reporting and methodological practices influenced study outcomes as well. These findings intimate tfMRI is a modest predictor of outcomes in left TLE that should be considered in the context of a larger surgical workup.

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Section: Discussionsupporting

confidence: 88%

Section: Discussionmentioning

confidence: 99%

mentioning

confidence: 92%

mentioning

confidence: 99%

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Task‐based functional magnetic resonance imaging prediction of postsurgical cognitive outcomes in temporal lobe epilepsy: A systematic review, meta‐analysis, and new data

et al. 2022

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“…In recent years, the Wada test has been used to predict the postoperative memory performance. While the availability of the memory Wada test has been supported by several reviews, the superiority of the classical Wada test over noninvasive tests has been questioned owing to various limitations ( Qadri et al, 2021 , Conradi et al, 2021 , Massot-Tarrús et al, 2020 ). The Wada test can only determine language lateralization and provides no information about within-hemisphere distribution.…”

Section: Introductionmentioning

confidence: 99%

Determination of language areas in patients with epilepsy using the super-selective Wada test

Kakinuma

Osawa

Hosokawa

et al. 2022

IBRO Neuroscience Reports

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Application value of molecular imaging technology in epilepsy

Rong

Zhang

Wang

et al. 2021

Ibrain

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Epilepsy is a common neurological disease with various seizure types, complicated etiologies, and unclear mechanisms. Its diagnosis mainly relies on clinical history, but an electroencephalogram is also a crucial auxiliary examination. Recently, brain imaging technology has gained increasing attention in the diagnosis of epilepsy, and conventional magnetic resonance imaging can detect epileptic foci in some patients with epilepsy. However, the results of brain magnetic resonance imaging are normal in some patients. New molecular imaging has gradually developed in recent years and has been applied in the diagnosis of epilepsy, leading to enhanced lesion detection rates. However, the application of these technologies in epilepsy patients with negative brain magnetic resonance must be clarified. Thus, we reviewed the relevant literature and summarized the information to improve the understanding of the molecular imaging application value of epilepsy.

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Concordance between fMRI and Wada test for memory lateralization in temporal lobe epilepsy: A meta-analysis and systematic review

Cited by 13 publications

References 27 publications

Task‐based functional magnetic resonance imaging prediction of postsurgical cognitive outcomes in temporal lobe epilepsy: A systematic review, meta‐analysis, and new data

Task‐based functional magnetic resonance imaging prediction of postsurgical cognitive outcomes in temporal lobe epilepsy: A systematic review, meta‐analysis, and new data

Determination of language areas in patients with epilepsy using the super-selective Wada test

Application value of molecular imaging technology in epilepsy

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