Hybrid timber-concrete (HTC) floor systems have gained wide acceptance within the structural engineering community as an alternative for reinforced concrete (RC) floor systems. They consist of a concrete layer and a timber layer acting predominantly in compression and tension, respectively. HTC floor systems are lightweight and with less embodied energy compared to RC floor systems. However, perfect composite action is difficult to achieve in HTC floor system resulting in part of the concrete layer acting in tension, thus reducing the material efficiency. In this thesis, an HTC floor system with a novel hollow core (called "HTCHC floor system" hereafter) is proposed. This novel floor system consists of a top concrete layer, bottom timber layer, and a fibre reinforced polymer (FRP)-timber hollow core sandwiched between them. Thickness of each layer is designed so that the bending neutral axis of the HTCHC floor panels is within the core, resulting in