Condensed Tannins from Mangrove Species Kandelia candel and Rhizophora mangle and Their Antioxidant Activity

Zhang, Liangliang; Lin, Yang; Zhou, Haichao; Wei, Shudong; Chen, Jiahong

doi:10.3390/molecules15010420

Cited by 98 publications

(80 citation statements)

References 29 publications

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“…Table 1 shows the average percent recovery and t obt for gallic acid, catechin, epicatechin, and procyanidin B2 to be 101. 58 [35]. For epicatechin and procyanidin B2, percent recoveries of 96.0 and 92.6% have been obtained, respectively, using Superspher ® 100 RP-18 (4 µm) cartridges (Merck) [38].…”

Section: Separation and Identification Of Phenolic Compounds By Chrommentioning

confidence: 99%

“…The infrared spectrum of Gallic acid (Cf 2 ) showed a stretching vibration of -OH at 3464. corresponding to a vibration of the O-H deformation. Mass spectrum (EIMS 70 eV) analysis of Cf 2 presents the molecular ion at m/z 170, coincident with the molecular formula of a phenolic acid such as Gallic acid (C 7 H 6 O 5 ), with a relative intensity of 100%, which also corresponds to the base peak, characteristic of phenols whose molecular ion peak is also its base [52][53][54][55][56][57][58][59][60][61][62] Tables 2 and 3 shows the Cf 2 mass spectrum data. Figures 5-7 shows the mass spectrum of Gallic acid.…”

Section: Separation and Identification Of Phenolic Compounds By Chrommentioning

confidence: 99%

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Isolation of Catechin and Gallic Acid from Colombian Bark of Pinus patula

Sarria-Villa¹,

Corredor²,

Páez³

2017

Chem Sci J

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Pine bark is a rich source of natural polyphenols, compounds which have attracted increasing attention in the fields of nutrition, health and medicine. Extractive components include large amounts of phenolic compounds. The ethanolic extract was obtained from Pinus patula bark grown in the forests of the Cauca Department in Colombia South America. The Gallic acid, catechin, epicatechin and procyanidin B2 contents in ethanolic extract were 3.12, 1.99, 0.80, and 0.71%, respectively, these compounds were determined using HPLC with UV-Vis detection. Ethanolic extract was divided using column chromatography to obtain an ethanol-soluble fraction with tannins and phlobaphenes as well as an ethanol-insoluble fraction mainly composed of Phenolic acids. Catechin and Gallic acid finally isolated were characterized using UV-Vis, IR, NMR, 13 C, 1 H, HSQC, HMBC and GC-MS spectrometry.

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Section: Separation and Identification Of Phenolic Compounds By Chrommentioning

confidence: 99%

Section: Separation and Identification Of Phenolic Compounds By Chrommentioning

confidence: 99%

Isolation of Catechin and Gallic Acid from Colombian Bark of Pinus patula

Sarria-Villa¹,

Corredor²,

Páez³

2017

Chem Sci J

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“…Ubiquitous bulk substances, such as chlorophyll and polyphenols (e.g., tannins) may interfere with biological assays and generate false positive or false negative results. Whereas chlorophyll was shown to interact with fatty acids and to possess anti-oxidative activity (Cho et al, 2000;Park et al, 2007;Potterat and Hamburger, 2006), tannins are known to form complexes with polysaccharides, proteins, and metal ions, to interfere with cell-based activity assays, and also to display antioxidative effects (Cos et al, 2006;Tan et al, 1991;Wei et al, 2011b;Zhang et al, 2010). …”

Section: Approaches For the Identification Of Active Plant Constituentsmentioning

confidence: 99%

Discovery and resupply of pharmacologically active plant-derived natural products: A review

2015

Draw Science

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Medicinal plants have historically proven their value as a source of molecules with therapeutic potential, and nowadays still represent an important pool for the identification of novel drug leads. In the past decades, pharmaceutical industry focused mainly on libraries of synthetic compounds as drug discovery source. They are comparably easy to produce and resupply, and demonstrate good compatibility with established high throughput screening (HTS) platforms. However, at the same time there has been a declining trend in the number of new drugs reaching the market, raising renewed scientific interest in drug discovery from natural sources, despite of its known challenges. In this survey, a brief outline of historical development is provided together with a comprehensive overview of used approaches and recent developments relevant to plant-derived natural product drug discovery. Associated challenges and major strengths of natural product- Europe PMC Funders Author ManuscriptsEurope PMC Funders Author Manuscripts based drug discovery are critically discussed. A snapshot of the advanced plant-derived natural products that are currently in actively recruiting clinical trials is also presented. Importantly, the transition of a natural compound from a "screening hit" through a "drug lead" to a "marketed drug" is associated with increasingly challenging demands for compound amount, which often cannot be met by re-isolation from the respective plant sources. In this regard, existing alternatives for resupply are also discussed, including different biotechnology approaches and total organic synthesis.While the intrinsic complexity of natural product-based drug discovery necessitates highly integrated interdisciplinary approaches, the reviewed scientific developments, recent technological advances, and research trends clearly indicate that natural products will be among the most important sources of new drugs also in the future.

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“…The leaves and bark extract of C. tagal shows antibacterial activity 65 . Phenolics are important components of the leaf extract and hypocotyls of K. candel and show excellent antioxidant activities 66,67 . Therefore, K. candel can be a good candidate for further development as an antioxidant medicine.…”

Section: Bioactivities Of Mangrove Extractsmentioning

confidence: 99%

Metabolites and bioactivities of Rhizophoraceae mangroves

Murukesh

Harisankar

Chandramohanakumar

2013

Nat. Prod. Bioprospect.

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This review examines the chemical compositions and bioactivities of mangrove plants belonging to the Rhizophoraceae family. The Rhizophoraceae family of true mangrove plants is the most common and is also widely distributed species. It consists of 24 species across four genera. Of the 24 species, 12 species remain unexamined for their phytochemical constituents. There have been 268 metabolites reported from 16 species. The key phytochemical constituents identified across the family are the diterpenoids and triterpenoids. The major diterpenoids include pimaranes, beyeranes, kaurenes, dolabranes and labdanes whereas the significant triterpenoids are lupanes, dammaranes and oleananes. Disulphides, dolabranes and labdanes are considered to be the chemotaxonomic markers of the genera Bruguiera, Ceriops and Rhizophora respectively.

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Condensed Tannins from Mangrove Species Kandelia candel and Rhizophora mangle and Their Antioxidant Activity

Cited by 98 publications

References 29 publications

Isolation of Catechin and Gallic Acid from Colombian Bark of Pinus patula

Isolation of Catechin and Gallic Acid from Colombian Bark of Pinus patula

Discovery and resupply of pharmacologically active plant-derived natural products: A review

Metabolites and bioactivities of Rhizophoraceae mangroves

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