Shibusawa et al 1 expressed interest in our work 2 and provided helpful comments about whether mean fluorescence intensity (MFI) and proportion of CD20 on leukemic cells at the baseline were well balanced between the two groups in the current study. 2 However, the information on MFI of CD20 was not routinely provided in our reports, and the characteristics of MFI and proportion of CD20 on leukemic cells were not taken into account when the patients were enrolled in this study.