Conduction in Abnormal Nerve

Brown, William F.

doi:10.1016/b978-0-409-95042-7.50007-4

Cited by 5 publications

(2 citation statements)

References 150 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Experimentally, FDB has been successfully demonstrated in animals8, 22–24, 32 and more recently in humans with multifocal motor neuropathy21 or chronic inflammatory demyelinating polyneuropathy 12. However, studies involving patients with entrapment neuropathies, such as carpal tunnel syndrome (CTS), resulting in conduction slowing from presumed myelin injury,10, 36 have failed to demonstrate this phenomenon despite stimulating the median nerve at frequencies in the order of 200 H Z 26, 33. Similar results have been observed in the thenar motor nerve fibers following voluntary contraction 13.…”

mentioning

confidence: 99%

Pigment cell distributions in different tissues of the zebrafish, with special reference to the striped pigment pattern

Hirata

Nakamura

Kondo

2005

Developmental Dynamics

125

121

View full text Add to dashboard Cite

The orderly pigment pattern of zebrafish (Danio rerio) is a good model system for studying how spatial patterns form in animals. Recent molecular genetic studies have shown that interactions between the pigment cells play major roles in pattern formation. In the present study, we performed comparative transmission electron microscopy of pigment cells, in order to clarify the structural interactions of pigment cells in tissues with and without a striped pattern. In patterned tissues, pigment cells were distributed as a one-cell-thick sheet. The layer order of the sheets is always kept strictly. In tissues without a striped pattern, the layer order was often disturbed or the cells were distributed in a scattered, double-sheeted, or an accumulated pile. Our observations suggest that the underlying mechanism that controls the vertical order of the pigment cells is related to that controlling the stripe pattern. Developmental Dynamics 234: 293-300, 2005.

show abstract

mentioning

confidence: 99%

Pigment cell distributions in different tissues of the zebrafish, with special reference to the striped pigment pattern

Hirata

Nakamura

Kondo

2005

Developmental Dynamics

125

121

View full text Add to dashboard Cite

show abstract

“…9 Experimentally, FDB has been successfully demonstrated in animals 8,[22][23][24]32 and more recently in humans with multifocal motor neuropathy 21 or chronic inflammatory demyelinating polyneuropathy. 12 However, studies involving patients with entrapment neuropathies, such as carpal tunnel syndrome (CTS), resulting in conduction slowing from presumed myelin injury, 10,36 have failed to demonstrate this phenomenon despite stimulating the median nerve at frequencies in the order of 200 Hz. 26,33 Similar results have been observed in the thenar motor nerve fibers following voluntary contraction.…”

mentioning

confidence: 99%

Frequency‐dependent conduction block in carpal tunnel syndrome

2006

Self Cite

View full text Add to dashboard Cite

Frequency-dependent conduction block (FDB) across segments of demyelination in response to high-frequency nerve stimulation has been well demonstrated in animals and has been explored in humans. However, attempts to demonstrate this phenomenon in sensory fibers involved in entrapment neuropathies have been unsuccessful. Therefore, we investigated the effects of high-frequency nerve stimulation in the median motor nerve in patients with carpal tunnel syndrome (CTS) with moderate to severely increased distal motor terminal latencies (MTL). As a group, the mean decrease in negative peak amplitude (npAmp) during 20 stimuli at 30-HZ frequency was significantly greater in CTS subjects (-11.3%) than in controls (+7.9%). The degree of FDB was greater when MTL was more prolonged (i.e., -4.9% at 5.0 ms and -25.3% at 9.4 ms) and FDB was more pronounced at higher stimulation frequencies (20 and 30 HZ). Our results suggest that the safety margin for impulse transmission is impaired in the motor axons of patients with a focal demyelinating lesion. These findings may correlate with the observation of weakness in the absence of conduction block in patients with entrapment neuropathies.

show abstract

The thoracic outlet syndromes

Ferrante

2012

Muscle and Nerve

View full text Add to dashboard Cite

The term thoracic outlet syndrome (TOS) refers to a heterogeneous group of disorders, all of which have in common compression of one or more neurovascular elements at some point within the thoracic outlet. Of the five disorders comprising this group, four have all of the features expected of a syndrome-a recognized constellation of clinical features; an anatomic derangement accounting for these features; and a method of testing that identifies the anatomic derangement. Consequently, their recognition and management are relatively straightforward. Conversely, one of these five disorders (nonspecific TOS) lacks these correlations, which has generated considerable debate in the literature and caused some experts to doubt its existence altogether. The primary focus in this study is on the neurologic forms of TOS. However, for completeness and a better understanding of these neurologic manifestations, the vascular forms are also reviewed.

show abstract

Conduction in Abnormal Nerve

Cited by 5 publications

References 150 publications

Pigment cell distributions in different tissues of the zebrafish, with special reference to the striped pigment pattern

Pigment cell distributions in different tissues of the zebrafish, with special reference to the striped pigment pattern

Frequency‐dependent conduction block in carpal tunnel syndrome

The thoracic outlet syndromes

Contact Info

Product

Resources

About