Conductive Keratoplasty: Histological Study of Human Corneas

The role of viscoelasticity and stress gradients on the outcome of conductive keratoplasty

“…More precisely, the analysis of the histology of a pig eye one week after CK treatment shows at each treatment spot a cylindrical footprint that extends to approximately 80% of the depth of midperipheral cornea (McDonald 2005). The treatment spots in the histopathological images of human corneae appear somewhat more homogenous and deeper (approximately 500 µm) than the cylindrical thermal footprint (Naoumidi et al 2005), but it can be nevertheless related to this shape. The new configuration is accompanied by contraction (shrinkage) of collagen that changes the mechanical behaviour of the tissue.…”

Two-year follow-up of conductive keratoplasty for the treatment of hyperopic astigmatism

“…Conductive keratoplasty (CK), a less-invasive procedure for the treatment of hyperopia and astigmatism, [19][20][21][22][23][24][25][26] does not involve flap creation and therefore flap-related complications, is nonlaser, produces a larger functional optical zone than LASIK, 24 significantly improves near vision, 25 and operates outside the central clear zone of the cornea.…”

“…1-11 However, many patients are not good candidates for a hyperopic laser procedure and might opt for a thermokeratoplasty treatment. [16][17][18][19][20][21][22][23][24][25][26][27][28] The considerations are either anatomical, such as small corneal diameter, excessively steep or flat cornea, 8 deep eye orbit, dry-eye syndrome, or epithelial basement membrane dystrophy, or psychological, such as fear of a corneal cut or the idea of corneal tissue removal.Conductive keratoplasty (CK), a less-invasive procedure for the treatment of hyperopia and astigmatism, [19][20][21][22][23][24][25][26] does not involve flap creation and therefore flap-related complications, is nonlaser, produces a larger functional optical zone than LASIK, 24 significantly improves near vision, 25 and operates outside the central clear zone of the cornea.With CK, high-frequency (radio frequency 350 kHz), low-energy current is delivered within the stroma of the peripheral cornea with a keratoplasty tip inserted in the cornea. 26 The technique uses electrical properties of the…”

“…[1][2][3][4][5][6][7][8][9][10][11] However, many patients are not good candidates for a hyperopic laser procedure and might opt for a thermokeratoplasty treatment. [16][17][18][19][20][21][22][23][24][25][26][27][28] The considerations are either anatomical, such as small corneal diameter, excessively steep or flat cornea, 8 deep eye orbit, dry-eye syndrome, or epithelial basement membrane dystrophy, or psychological, such as fear of a corneal cut or the idea of corneal tissue removal.…”

“…[16][17][18][19][20][21][22][23][24][25][26][27][28] The considerations are either anatomical, such as small corneal diameter, excessively steep or flat cornea, 8 deep eye orbit, dry-eye syndrome, or epithelial basement membrane dystrophy, or psychological, such as fear of a corneal cut or the idea of corneal tissue removal.…”