2023
DOI: 10.1101/2023.10.21.563390
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CONE: COntext-specific Network Embedding via Contextualized Graph Attention

Renming Liu,
Hao Yuan,
Kayla A Johnson
et al.

Abstract: Human gene interaction networks, commonly known as interactomes, encode genes functional relationships, which are invaluable knowledge for translational medical research and the mechanistic understanding of complex human diseases. Meanwhile, the advancement of network embedding techniques has inspired recent efforts to identify novel human disease-associated genes using canonical interactome embeddings. However, one pivotal challenge that persists stems from the fact that many complex diseases manifest in spec… Show more

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