The iMeta Conference 2024, held from October 11 to 13, 2024, at the Nanshan District People's Hospital in Shenzhen, China, attracted over 400 leading scientists, researchers, and industry professionals from around the world (File S1). Organized by the editorial team of iMeta, a top-tier interdisciplinary journal in biotechnology, microbiome, and bioinformatics, this conference has been emerging as a premier platform for cutting-edge research in these fields. The iMeta journal, led by Chief Editors Prof. Shuangjiang Liu and Prof. Jingyuan Fu, has an impressive impact factor of 23.8, within the top 0.5% of journals worldwide (107 out of 21,848), and 11th in mainland China. Additionally, iMetaOmics, a subjournal co-edited by Prof. Fangqing Zhao and Prof. Jun Yu, is projected to have an impact factor of over 10, positioning it as a high-level interdisciplinary journal that welcomes submissions [1].Since its inception in 2022, the iMeta journal has launched a series of conferences aimed at advancing research, fostering international collaboration, and promoting the development of the field [2]. Following successful events in Qingdao and Beijing [3], the 2024 edition marks the third event in this series that was