Conference Scene: Novelties in Immunotherapy

Abstract

The only method aiming to permanently cure allergic disorders is allergen immunotherapy. Over the last 20 years there has been great progress in understanding the mechanisms that govern allergen immunotherapy in order to meet three basic prerequisites: safety, effectiveness and compliance. In the present summary report from the European Academy of Allergology and Clinical Immunology-World Allergy Organization Congress held last June in Milan, we review key points concerning the main axes as diagnosis, novel modalities, routes and protocols, as well as two important immunotherapy fields: food and insect venom allergy.

Immunotherapy in allergy and cellular tests

“…115,133 Well designed, prospective clinical trials are urgently needed to determine whether OIT is a safe, effective form of therapy for food allergy. 120,121,134,135 In food allergy, immunotherapy is usually performed by oral or sublingual administration of allergens: several research studies have assessed that oral and sublingual immunotherapy for food allergy is generally well-tolerated and safe in highly controlled clinical settings. [136][137][138][139][140] Reports from the NIAID-sponsored Expert Panel provided concise clinical recommendations and additional guidance on points of current controversy in patient management about food allergy and immunotherapy, yet identifying gaps in the current scientific knowledge to be addressed through future research in the field.…”