Psychological studies of treatment adherence have established: 1) indica- tor models—requency of consultation, the prevalence of medication intake over any other treat- ment, attendance at therapeutic and rehabilitation sessions—; 2) determining models—sex, age, income, level of education, reading comprehension, interpersonal relationships—; 3) mediating mod- els—beliefs, attitudes, knowledge, intentions, and strategies—. Objective: to establish categories for the study of treatment adherence in literature published between 2015–2019, considering the occupational health climate. Method: secondary research using a selection of 38 indexed sources in Latin American repositories—Dialnet, Latindex, Publindex, Redalyc, and Scielo—and the variables reported in the state of the art. Results: the model specification included four explanatory hypotheses of dependence relationship trajectories of six variables—demands, social support, control, effort, reward, and adherence—taken from the literature review. Discussion: regarding the indicator, determining, and mediating models, we recommend including the work culture, quality of life, and subjective well-being variables in the specified model to examine the process that goes from the workplace culture to reinserting workers after accidents and diseases. Conclusion: the new model specification would include explanatory hypotheses of variable correlation trajectories to establish differences between organizations that provide social security and companies with workplace flexibility and their effects on their workers’ occupational health.