Configurational patterns for COVID-19 related social media rumor refutation effectiveness enhancement based on machine learning and fsQCA

Li, Zongmin; Zhao, Yanli; Duan, Tie; Dai, Jindong

doi:10.1016/j.ipm.2023.103303

Cited by 10 publications

(1 citation statement)

References 67 publications

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“…LGBM [47] is a gradient-boosting framework based on decision tree algorithms; it offers lower memory usage and faster training speed. The parameters of the best model that we used were as follows: 'max depth': 9, 'n_estimators': 750, 'learning rate': 0.05.…”

Section: Algorithmsmentioning

confidence: 99%

A Stacking Machine Learning Method for IL-10-Induced Peptide Sequence Recognition Based on Unified Deep Representation Learning

Li,

Jiang,

Pei

et al. 2023

Applied Sciences

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Interleukin-10 (IL-10) has anti-inflammatory properties and is a crucial cytokine in regulating immunity. The identification of IL-10 through wet laboratory experiments is costly and time-intensive. Therefore, a new IL-10-induced peptide recognition method, IL10-Stack, was introduced in this research, which was based on unified deep representation learning and a stacking algorithm. Two approaches were employed to extract features from peptide sequences: Amino Acid Index (AAindex) and sequence-based unified representation (UniRep). After feature fusion and optimized feature selection, we selected a 1900-dimensional UniRep feature vector and constructed the IL10-Stack model using stacking. IL10-Stack exhibited excellent performance in IL-10-induced peptide recognition (accuracy (ACC) = 0.910, Matthews correlation coefficient (MCC) = 0.820). Relative to the existing methods, IL-10Pred and ILeukin10Pred, the approach increased in ACC by 12.1% and 2.4%, respectively. The IL10-Stack method can identify IL-10-induced peptides, which aids in the development of immunosuppressive drugs.

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Section: Algorithmsmentioning

confidence: 99%