Confirmation and Analysis of<i>s</i>-Chlorotriazines by Derivatization with Pyrrolidine

Thio, Alan P.; Kornet, Milton J.

doi:10.1080/00032719508001126

Cited by 3 publications

(2 citation statements)

References 36 publications

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“…A detailed description of the properties of triazine derivatives is compiled in a classic monograph 56, 57. A great deal of effort has been made to detect and elucidate the degradation pathways of triazine‐based herbicides,58, 59 reactive dyes,60 plastics, and triazine‐based explosives. Several of those measures can be successfully applied in order to resolve problems caused by application of TBCR in organic synthesis.…”

Section: Preparation and Properties Of Tbcrsmentioning

confidence: 99%

Triazine-based condensing reagents

Kamiński

2000

Biopolymers

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The synthesis, properties, and application of condensing reagents derived from 1,3,5‐triazines are described. The mechanism of activation of carboxylic function, structure of reactive intermediates, and mechanism of acylation of nucleophiles are presented. The synthetic versatility of mono‐ and bifunctional reagents for syntheses in solution, triazine‐based immobilized reagents, chiral triazines for enantiodifferentiating syntheses, are discussed. The scope and limitation of the synthetic utility of triazine reagents in the preparation of heterocyclic compounds, amides, esters, oligopeptides—including large‐scale syntheses and use in the combinatorial chemistry—is demonstrated. ©:2000 John Wiley & Sons, Inc. Biopoly 55: 140–164, 2000

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Section: Preparation and Properties Of Tbcrsmentioning

confidence: 99%

Triazine-based condensing reagents

Kamiński

2000

Biopolymers

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“…The wide application of triazine herbicide resulted in the U.S. EPA imposing limits on environmental matrixes, including drinking water and underground water. Gas chromatography is a very efficient method for atrazine (Figure ) analysis, but the polar degradation products, such as hydroxyatrazine, must be derivatized prior to GC analysis …”

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Comparison of Reversed-Phase HPLC Separation Using Carbon Dioxide and Fluoroform for Enhanced-Fluidity Liquid Mobile Phases

Yuan

Olesik

1998

Anal. Chem.

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Lowering the viscosity of an HPLC mobile phase using liquid CO2/organic solvent mixtures has proven to be an effective means of increasing chromatographic efficiency, shortening analysis time, and lowering the pressure drop under ambient conditions. Such mixtures easily retain the high solvating power of common organic solvents but have low viscosities that are similar to those of supercritical fluids. To overcome the disadvantages of CO2 such as acidity in aqueous solution and reactivity toward some basic analytes, liquid mixtures of CHF3/methanol/H2O are investigated in HPLC separations. Triazine herbicides were used as the test solutes for reversed-phase HPLC. While either CO2- or CHF3-containing (20 mol %) enhanced-fluidity mobile phase provided better efficiency, shorter analysis time, and lower pressure drop than the methanol/H2O mobile phase, the mobile phase containing CHF3 was superior to that with CO2 in chromatographic performance. CO2 also influences the pH of the water-containing mobile phase, which results in resolution loss for some analytes with high pK as. The addition of a 10 mM phosphate buffer improved the efficiency for all the mobile phases, either with or without CO2 or CHF3, which affirms the importance of maintaining pH for ionizable analytes in reversed-phase HPLC using either common or enhanced-fluidity liquid mobile phase. The strongest enhancement in chromatographic performance was provided by the CHF3-containing mobile phase with buffer.

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