Confluent hepatic fibrosis in liver cirrhosis: possible relation with middle hepatic venous drainage

Ozaki, Kumi; Matsui, Osamu; Gabata, Toshifumi; Kobayashi, Satoshi; Koda, Wataru; Minami, Tetsuya

doi:10.1007/s11604-013-0222-8

Cited by 12 publications

(6 citation statements)

References 29 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…However, while mICC presents as a lobulated lesion associated with capsular retraction, focal confluent fibrosis is typically seen as a wedge-shaped lesion radiating from the porta hepatis with straight or concave borders and the base in the subcapsular region [ 15 , 30 ]. Focal confluent fibrosis commonly involves segments IV, VII, or VIII corresponding to the drainage territory of the middle hepatic vein [ 32 , 33 ]. Dilatation of proximal intrahepatic biliary ducts is frequently seen in mICC, whereas it is not observed in focal confluent fibrosis [ 15 ].…”

Section: Mimickers Of Mass-forming Icc On Mrimentioning

confidence: 99%

Imaging Spectrum of Intrahepatic Mass-Forming Cholangiocarcinoma and Its Mimickers: How to Differentiate Them Using MRI

et al. 2022

View full text Add to dashboard Cite

Intrahepatic cholangiocarcinoma (ICC) is the second most common primary hepatic malignancy, with mass-forming growth pattern being the most common. The typical imaging appearance of mass-forming ICC (mICC) consists of irregular ring enhancement in the arterial phase followed by the progressive central enhancement on portal venous and delayed phases. However, atypical imaging presentation in the form of hypervascular mICC might also be seen, which can be attributed to distinct pathological characteristics. Ancillary imaging features such as lobular shape, capsular retraction, segmental biliary dilatation, and vascular encasement favor the diagnosis of mICC. Nevertheless, these radiological findings may also be present in certain benign conditions such as focal confluent fibrosis, sclerosing hemangioma, organizing hepatic abscess, or the pseudosolid form of hydatid disease. In addition, a few malignant lesions including primary liver lymphoma, hemangioendothelioma, solitary hypovascular liver metastases, and atypical forms of hepatocellular carcinoma (HCC), such as scirrhous HCC, infiltrative HCC, and poorly differentiated HCC, may also pose a diagnostic dilemma by simulating mICC in imaging studies. Diffusion-weighted imaging and the use of hepatobiliary contrast agents might be helpful for differential diagnosis in certain cases. The aim of this manuscript is to provide a comprehensive overview of mICC imaging features and to describe useful tips for differential diagnosis with its potential mimickers.

show abstract

Section: Mimickers Of Mass-forming Icc On Mrimentioning

confidence: 99%

Imaging Spectrum of Intrahepatic Mass-Forming Cholangiocarcinoma and Its Mimickers: How to Differentiate Them Using MRI

et al. 2022

View full text Add to dashboard Cite

show abstract

“…Herein, 62 studies [ 14 – 16 , 18 – 20 , 22 – 25 , 29 – 31 , 33 – 40 , 44 – 46 , 50 , 53 , 55 , 56 , 58 – 60 , 63 – 67 , 71 , 77 , 78 , 80 , 81 , 84 – 86 , 92 , 93 , 96 , 97 , 99 – 101 , 104 – 107 , 111 ] were included to analyze the influence of sex on the prevalence of ARLD. The prevalence of male was 2.9% (95% CI: 2.4–3.5), which was much higher than that of women (0.5%, 95% CI: 0.4–0.7) (Table 1 ).…”

Section: Resultsmentioning

confidence: 99%

“…In order to further analyze the changes in the global ARLD prevalence in different periods, seventy three articles indicating the study years were included. From these, 48 articles [ 10 , 20 , 25 , 26 , 30 , 34 , 35 , 37 , 40 , 42 – 44 , 48 , 50 , 53 , 59 – 63 , 67 – 69 , 71 – 74 , 76 , 80 , 81 , 83 , 85 , 87 – 91 , 93 – 97 , 99 – 102 , 109 , 111 ] were used for subgroup analysis of the prevalence from 2000 to 2010: 4.6% (95% CI: 4.2–5.1) (Table 1 ). A total of 18 articles [ 10 , 17 , 19 , 22 , 26 , 41 , 43 , 49 , 51 , 52 , 65 , 70 , 75 , 78 , 79 , 82 , 104 , 106 ] were used to analyze the prevalence in 2011–2021, and the result was 5.6% (95% CI: 2.4–10.1), which was significantly higher in this period than in 2000–2010 (Table 1 ).…”

Section: Resultsmentioning

confidence: 99%

Global prevalence, incidence, and outcomes of alcohol related liver diseases: a systematic review and meta-analysis

Niu

Zhu

et al. 2023

BMC Public Health

View full text Add to dashboard Cite

Background Alcohol related liver disease (ARLD) is one of the major chronic liver diseases worldwide. This review aimed to describe the global prevalence, incidence, and outcomes of ARLD. Methods Medline, Embase, The Cochrane Library, and China National Knowledge Infrastructure (CNKI) were searched from inception to May 31, 2022. The language was restricted to English or Chinese. According to the criteria, articles describing the basic characteristics of the population were selected. Two reviewers extracted the data independently. Results A total of 372 studies were identified: 353 were used for prevalence analysis, 7 were used for incidence analysis, and 114 were used to for outcome analysis. The prevalence of ARLD worldwide was 4.8%. The prevalence in males was 2.9%, which was higher than female (0.5%). Among the ethnic groups, the percentage was highest in Caucasians (68.9%). Alcoholic liver cirrhosis comprised the highest proportion in the disease spectrum of ARLD at 32.9%. The prevalence of ascites in ARLD population was highest (25.1%). The ARLD population who drinking for > 20 years accounted for 54.8%, and the average daily alcohol intake was 146.6 g/d. About 59.5% of ARLD patients were current or former smokers, and 18.7% were complicated with hepatitis virus infection. The incidence was 0.208/1000 person-years. The overall mortality was 23.9%, and the liver-related mortality was 21.6%. Conclusion The global prevalence of ARLD was 4.8% and was affected by sex, region, drinking years, and other factors. Therefore, removing the factors causing a high disease prevalence is an urgent requisite. Trial registration PROSPERO Nr: CRD42021286192

show abstract

“…Confluent fibrosis often demonstrates a characteristic appearance at MRI. These lesions are typically peripheral and subcapsular, and often arise in the central liver segments, 4,5,8 corresponding to the drainage territory of the middle hepatic vein 75 . Unlike malignant tumors, confluent fibrosis is wedge‐shaped or band‐like, with straight or concave borders.…”

Section: Pseudotumors In Chronic Liver Diseasementioning

confidence: 99%

Benign Neoplasms, Mass‐Like Infections, and Pseudotumors That Mimic Hepatic Malignancy at MRI

Costa

Clarke

Stueck

et al. 2020

Magnetic Resonance Imaging

View full text Add to dashboard Cite

A variety of conditions may mimic hepatic malignancy at MRI. These include benign hepatic tumors and tumor‐like entities such as focal nodular hyperplasia‐like lesions, hepatocellular adenoma, hepatic infections, inflammatory pseudotumor, vascular entities, and in the cirrhotic liver, confluent fibrosis, and hypertrophic pseudomass. These conditions demonstrate MRI features that overlap with hepatic malignancy, and can be challenging for radiologists to diagnose accurately. In this review we discuss the MRI manifestations of various conditions that mimic hepatic malignancy, and highlight features that may allow distinction from malignancy. Level of Evidence5 Technical Efficacy Stage3

show abstract

Confluent hepatic fibrosis in liver cirrhosis: possible relation with middle hepatic venous drainage

Cited by 12 publications

References 29 publications

Imaging Spectrum of Intrahepatic Mass-Forming Cholangiocarcinoma and Its Mimickers: How to Differentiate Them Using MRI

Imaging Spectrum of Intrahepatic Mass-Forming Cholangiocarcinoma and Its Mimickers: How to Differentiate Them Using MRI

Global prevalence, incidence, and outcomes of alcohol related liver diseases: a systematic review and meta-analysis

Benign Neoplasms, Mass‐Like Infections, and Pseudotumors That Mimic Hepatic Malignancy at MRI

Contact Info

Product

Resources

About