Conformational analysis of lipid membrane mimetics modified with A
            <i>β42</i>
            peptide by Raman spectroscopy and computer simulations

Mamatkulov, Kahramon; Zavatski, Siarhei; Arynbek, Yersultan; Esawii, Heba A.; Burko, Aliaksandr; Bandarenka, Hanna; Arzumanyan, Grigory

doi:10.1080/07391102.2024.2330706

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Variants Of Raman Spectroscopy and Microscopy Techniques2

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2024

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“…Conventional RS serves as a valuable tool for identifying and characterizing biomolecules such as proteins, lipids, and nucleic acids implicated in brain disorders. 44,53,54 This is an inelastic scattering process where a molecule in the ground state interacts with an incident photon, and the resulting scattered photon has a different energy (frequency) from the incident photon. The energy difference corresponds to the vibrational energy levels of the molecule.…”

Section: Variants Of Raman Spectroscopy and Microscopy Techniquesmentioning

confidence: 99%

“…In addition, this technique has been instrumental in exploring changes in lipid and protein composition observed in AD, PD, and other brain disorders. 54,55 By probing the vibrational modes of biomolecules, conventional RS provides molecular-specific information, thereby elucidating alterations in molecular composition, structure, and interactions associated with brain disorders.…”

Section: Variants Of Raman Spectroscopy and Microscopy Techniquesmentioning

confidence: 99%

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