Congenital Absence of the Gall-Bladder

Bower, John O.

doi:10.1097/00000658-192807000-00010

Cited by 18 publications

(4 citation statements)

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“…Gallbladder agenesis without extrahepatic biliary atresia is a rare congenital anomaly. Since this abnormality was first described in 1701, several cases have been reported, and most cases of gallbladder agenesis have been asymptomatic . Preoperative diagnosis of gallbladder agenesis has been considered very difficult because abdominal ultrasonography (US) or computed tomography (CT) may not distinguish an absent gallbladder from one shrunken by inflammation.…”

Section: Introductionmentioning

confidence: 99%

Gallbladder agenesis with a stone in the cystic duct bud

Ishida

Egawa

Takahashi³

et al. 2008

J Hepatobiliary Pancreat Surg

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An 84-year-old woman was admitted to the hospital because of pyloric stenosis caused by gastric cancer. Abdominal computed tomography and magnetic resonance imaging failed to demonstrate the gallbladder, but showed a gallstone in a duct-like structure parallel to the common bile duct. When laparotomy was performed, the gallbladder and the fossa were not observed, and a blind-end duct, similar to a cystic duct, was found beside the common bile duct. Incisional exploration of the common bile duct was done after distal gastrectomy; the gallstone was not found in the common bile duct, but in the duct parallel to it. By observing the duct beneath the common bile duct with a cholangioscope, we considered it to be a hypoplastic cystic duct. After the gallstone was removed, a T-tube was placed into the common bile duct. Agenesis of the gallbladder is a rare congenital anomaly and is often asymptomatic. As far as we know, this is the first report of gallbladder agenesis with a hypoplastic cystic duct impacted with a stone. Careful intraoperative examination using a cholangioscope is useful to confirm the structure of the common bile duct.

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Section: Introductionmentioning

confidence: 99%

Gallbladder agenesis with a stone in the cystic duct bud

Ishida

Egawa

Takahashi³

et al. 2008

J Hepatobiliary Pancreat Surg

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“…Congenital gallbladder agenesis is a very rare situation [1][2][3]. Low clinical suspicion and inability of routine investigation to demonstrate this situation often leads to misdiagnosis and to a stressful procedure for the laparoscopic surgeon [14].…”

Section: Resultsmentioning

confidence: 99%

“…Most individuals remain asymptomatic for life. This abnormality was described in 1701 [3] and since 2003, 413 cases have been reported in the literature [4]. To date, more than 10 new cases have been reported [5-10].…”

Section: Introductionmentioning

confidence: 99%

Congenital agenesis of the gallbladder: An unpleasant surprise during laparoscopic cholecystectomy

et al. 2010

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Background: Congenital gallbladder agenesis is a rare anomaly of the biliary tree. This asymptomatic situation is sometimes complicated with symptoms mimicking "gallbladder disease". This case presentation shows the importance of a thorough preoperative investigation in order to avoid the increased risk of iatrogenic injury to the biliary tree. Case report: A 45-year old woman consulted her surgeon complaining of right upper quadrant pain, which was precipitated by fatty meals. After routine ultrasound investigation, she was scheduled for laparoscopic cholecystectomy. During the operation, there was no evidence of a gallbladder, even after thorough dissection of the porta hepatis. The procedure was terminated and postoperative MRCP confirmed the diagnosis of gallbladder absence. Conclusion: Gallbladder absence is a very rare congenital abnormality of the biliary tree. During laparoscopy, thorough dissection of Callot's triangle increases the risk of iatrogenic injury. Preoperative advanced imaging studies are needed when routine investigation is equivocal.

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“…Agenesis of the gallbladder and cystic duct is a rare congenital condition that results from the failure of the cystic bud to develop in the 4 th week of intrauterine life, and it has a reported incidence of 13–65 per 100 000 population [ 3 ]. It was first described in 1701 [ 4 ]. Choledocholithiasis has been reported to occur in 18% to 50% of patients with gallbladder agenesis, and all have jaundice as the first presentation [ 5 – 9 ].…”

Section: Introductionmentioning

confidence: 99%

Gallbladder agenesis with a primary choledochal stone in a patient with situs inversus totalis

Alzahrani

Yamani

2014

Am J Case Rep

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Patient: Female, 68Final Diagnosis: Gallbladder agenesis with situs inversus totalisSymptoms: Epigastric pain • jaundiceMedication: —Clinical Procedure: —Specialty: SurgeryObjective:Rare diseaseBackground:Situs inversus totalis is an inherited condition characterized by the mirror-image transposition of thoracic and abdominal organs. Gallbladder agenesis, which has normal bile ducts, is a rare congenital condition that occurs in 13 to 65 people out of 100 000. A common bile duct (CBD) stone or choledocholithiasis in patients with gallbladder agenesis is even rarer.Case Report:We report the case of a 68-year-old woman who presented with epigastric pain and jaundice. She was not known to have situs inversus totalis. Abdominal ultrasound showed a large stone in the CBD, which could not be extracted by endoscopic retrograde cholangiopancreatography (ERCP), necessitating exploration. The gall-bladder and cystic duct were found to be absent. Incisional exploration of the CBD was performed, and a large stone was removed. A choledochoscope was used to identify the remnants and exclude the presence of ectopic gallbladder, and a T-tube was placed into the CBD.Conclusions:Gallbladder agenesis in a patient with situs inversus totalis is extremely rare, with no single reported case identified in the literature. In addition, our case showed a rare complication of ERCP – a failure to extract the CBD stone – and illustrates a way to overcome this complication.

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Congenital Absence of the Gall-Bladder

Cited by 18 publications

References 0 publications

Gallbladder agenesis with a stone in the cystic duct bud

Gallbladder agenesis with a stone in the cystic duct bud

Congenital agenesis of the gallbladder: An unpleasant surprise during laparoscopic cholecystectomy

Gallbladder agenesis with a primary choledochal stone in a patient with situs inversus totalis

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