Congenital absence of the vagina—the mayer-rokitansky-kuster-hauser syndrome

Bergh, Paul A.; Breen, James; Gregori, Caterina A.

doi:10.1016/s0932-8610(89)80046-5

Cited by 9 publications

(4 citation statements)

References 81 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The incidence is about 1 in 4000–5000 live female births. [ 1 2 3 4 5 ] Vaginal agenesis has serious implications on the sexual life of women. Many techniques have been described for vagina reconstruction.…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Comparison of modified McIndoe and Davydov vaginoplasty in patients with MRKH syndrome in terms of anatomical results, sexual performance and satisfaction

Shokrpour

Deldar-Pesikhani

Ghanbari

et al. 2022

Journal of Family Medicine and Primary Care

View full text Add to dashboard Cite

Introduction: To compare the modified McIndoe versus Davydov vaginoplasty techniques in terms of anatomical results, sexual performance, and satisfaction. Methods: From September 2019 to June 2021, a comparative study was conducted on 20 patients with MRKH syndrome who underwent either McIndoe vaginoplasty (McIndoe group, 10 cases) or Davydov vaginoplasty (Davydov group, 10 cases) in a university-based tertiary care hospital (Imam Khomeini Hospital) in terms of anatomical results, sexual performance, and satisfaction. Functional results were assessed using the Female Sexual Function Index (FSFI). Results: All surgical procedures (n = 20) were performed successfully. Patients in the modified McIndoe group were similar to those in the Davydov group in terms of hospital stay and intraoperative complications. However, postoperative complications were higher in the McIndoe group. There were no significant differences in the neovaginal length and width of the two groups at the 6-month follow-up ( P > 0.05). Other parameters (duration of mold use and blood transfusion) were similar for all patients in the two groups. At 12 months after surgery, all patients had regular sexual activity. No significant differences were found in either group. Conclusions: In terms of anatomical results, sexual performance, and satisfaction, the two techniques were similar.

show abstract

Section: Discussionmentioning

confidence: 99%

“…About 7%–10% of patients also have functional uterine remnant horn, which can cause cyclic pain. [ 4 5 ] Treatment of MRKH syndrome involves constructing a neovagina with appropriate longitudinal and horizontal size to enable satisfactory intercourse. Both the nonsurgical and surgical modes of creating a vagina are described.…”

Section: Introductionmentioning

confidence: 99%

Comparison of modified McIndoe and Davydov vaginoplasty in patients with MRKH syndrome in terms of anatomical results, sexual performance and satisfaction

Shokrpour

Deldar-Pesikhani

Ghanbari

et al. 2022

Journal of Family Medicine and Primary Care

View full text Add to dashboard Cite

show abstract

“…Most of the patient have rudimentary uterus which are nonfunctional while 7-10% may have functional endomentrium. 4 The principal aim of the treatment is to restore the sexual function by creating a vaginal canal at the normal anatomical position and axis. This neovaginal canal is created within an avascular space between the urethra and bladder above and the rectum below.…”

Section: Figure 2: Preparation Of Mould and Amnionmentioning

confidence: 99%

Amnion Graft Vaginoplasty in Vaginal Agenesis

Poudel

Dangal

2021

JCMC

View full text Add to dashboard Cite

Vaginal agenesis seen in Mayer-Rokitansky-Kuster-Hauser (MRKH) syndrome is a condition with significant psychological and social consequences where there is embryonic underdevelopment of müllerian duct. It is estimated to occur one in 4000 to 5000 live births. Normalizing sexual life with vaginal reconstruction to adequate length is usually the treatment of choice. Among many non-surgical and surgical options available, McIndoe vaginoplasty is the commonest surgical management performed worldwide with various modifications, like the use of amnion as a graft. A 19-year-old girl with normal secondary sexual characters came with vaginal agenesis with hypoplastic uterus. MRI revealed streak like structure over the pelvis with imperforate hymen and atresia of the vagina. Surgical intervention included creation of vaginal canal from a potential space between urethra and bladder above and rectum below and a fresh amnion mounted mould was placed within the canal. The amnion graft was seen well taken with resultant 4 to 5 cm of vaginal canal when mould was removed 10 days later. She was counselled and taught to remove and insert the mould to prevent vaginal narrowing and maintain the length. Amnion graft vaginoplasty has with good success rate with minimal postoperative pain, infection and scarring and thus is a rewarding procedure especially in low resource countries.

show abstract

“…Vaginal agenesis is reported to have an incidence of 1 in 5,000, with most having cervical or uterine agenesis, although 7%-10% have some degree of M€ ullerian formation (4)(5)(6), with 2%-7% having functional endometrium leading to abdominal pain secondary to hematocolpos, hematometra, hematosalpinx, or endometriosis (7,8). Selective agenesis of the lower vagina, segmental agenesis, or vaginal atresia is a separate entity managed in a different manner and has been associated with normal M€ ullerian development, although it may be a form that exists on a continuum of vaginal agenesis (9).…”

mentioning

confidence: 99%