Congenital bony nasal cavity stenosis: A review of current trends in diagnosis and treatment

Galluzzi, Francesca; Garavello, Werner; Dalfino, Gianluca; Castelnuovo, Paolo; Turri‐Zanoni, Mario

doi:10.1016/j.ijporl.2021.110670

Cited by 9 publications

(2 citation statements)

References 65 publications

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“…While choanal atresia/stenosis is a common cause of pediatric nasal obstruction (Smith & Ishman, 2018), it is a relatively rare condition with prevalence estimates on the order of 0.8–0.9/10,000 births (Case & Mitchell, 2011; Harris et al, 1997). The pathogenesis of choanal atresia/stenosis is not known (Galluzzi et al, 2021; Kurosaka, 2019).…”

Section: Introductionmentioning

confidence: 99%

Prevalence and descriptive epidemiology of choanal atresia and stenosis in Texas, 1999–2018

Benjamin,

Marengo,

Scheuerle

et al. 2024

American J of Med Genetics Pt A

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Choanal atresia and stenosis are common causes of congenital nasal obstruction, but their epidemiology is poorly understood. Compared to bilateral choanal atresia/stenosis, unilateral choanal atresia/stenosis is generally diagnosed later and might be under‐ascertained in birth defect registries. Data from the population‐based Texas Birth Defects Registry and Texas vital records, 1999–2018, were used to assess the prevalence of choanal atresia/stenosis. Poisson regression models were used to evaluate associations with infant and maternal characteristics in two analytic groups: isolated choanal atresia/stenosis (n = 286) and isolated, bilateral choanal atresia/stenosis (n = 105). The overall prevalence of choanal atresia/stenosis was 0.92/10,000, and the prevalence of isolated choanal atresia/stenosis was 0.37/10,000 livebirths. Variables associated with choanal atresia/stenosis in one or both analytic groups included infant sex, pregnancy plurality, maternal race/ethnicity, maternal age, and maternal residence on the Texas–Mexico border. In general, adjusted prevalence ratios estimated from the two analytic groups were in the same direction but tended to be stronger in the analyses restricted to isolated, bilateral defects. Epidemiologic studies of isolated choanal atresia/stenosis should consider focusing on cases with bilateral defects, and prioritizing analyses of environmental, social, and structural factors that could account for the association with maternal residence on the Texas–Mexico border.

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Section: Introductionmentioning

confidence: 99%

Prevalence and descriptive epidemiology of choanal atresia and stenosis in Texas, 1999–2018

Benjamin,

Marengo,

Scheuerle

et al. 2024

American J of Med Genetics Pt A

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“…Laut Sohal et al kann die mittlere nasalen Stenose durch eine angeborene Verdickung der Nasenscheidewand oder eine knöcherne Verengung der Nasenhöhle selbst entstehen [7]. Die Engstelle liegt zwischen dem Nasenseptum und der unteren Nasenmuschel [8].…”

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Midnasale Stenose: Eine seltene Differenzialdiagnose zur Choanalatresie

Rovas

Mand

Mueller

et al. 2022

Laryngorhinootologie

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In diesem Beitrag berichten wir über ein männliches Neugeborenes mit der sehr seltenen Fehlbildung einer angeborenen mittleren nasalen Stenose (engl.: midnasal stenosis; MNS) im Rahmen einer Deletion-Duplikations-Mutation auf Chromosom 7. Nach Ausschluss der häufigsten Ursachen rezidivierender zyanotischer Episoden, vor allem während der Nahrungsaufnahme, wurde mittels nasaler Endoskopie und einer Computertomografie die Diagnose einer MNS gestellt. Da die konservative Therapie keine Besserung erbrachte, erfolgte die operative Behandlung im Sinne einer Bougierung des unteren und mittleren Nasenganges einschließlich des Einsetzens von beidseitigen Stents, die zu einer anhaltenden Besserung der Beschwerden führte.

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Heated humidified high-flow nasal cannula: a new conservative approach for neonatal nasal stenosis

Havazelet,

Stafler,

Zarzur

et al. 2024

Eur Arch Otorhinolaryngol

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Purpose The aim of this study is to evaluate the efficacy of heated humidified high flow nasal cannula (HFNC) therapy as a conservative treatment option for newborns suffering from nasal stenosis, a condition that often leads to respiratory distress and feeding difficulties. Given the increasing utilization of HFNC in various upper and lower respiratory tract indications, characterized by its flow-based mechanism and minimal mucosal damage, we seek to investigate its potential benefits in this specific patient population. Methods A retrospective chart review of newborns with congenital nasal stenosis treated with HFNC for respiratory distress or feeding difficulties in a pediatric tertiary center between 2014 and 2022. Data were collected for demographic characteristics, clinical presentation and ventilatory requirements, pre and post HFNC application. Results Six infants with nasal stenosis were included in the study cohort. Five were diagnosed with congenital pyriform aperture stenosis, three of whom had additional midnasal stenosis. One patient had nasal synechiae. Two patients had failed surgical treatment and all patients failed conservative treatment prior to HFNC treatment. Following HFNC use, improvement was noted in oxygen saturations, heart and respiratory rates, meal volumes and weight. None of the patients required any additional sinonasal surgical treatment. No complications were observed. Conclusions In this case series, we present the first documented use of HFNC treatment for nasal stenosis, showing favorable results. Further studies with a larger cohort, wider range of conditions and extended follow-up periods are needed to establish the risks and benefits of HFNC for neonatal nasal stenosis.

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Congenital bony nasal cavity stenosis: A review of current trends in diagnosis and treatment

Cited by 9 publications

References 65 publications

Prevalence and descriptive epidemiology of choanal atresia and stenosis in Texas, 1999–2018

Prevalence and descriptive epidemiology of choanal atresia and stenosis in Texas, 1999–2018

Midnasale Stenose: Eine seltene Differenzialdiagnose zur Choanalatresie

Heated humidified high-flow nasal cannula: a new conservative approach for neonatal nasal stenosis

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