2018
DOI: 10.1089/vbz.2018.2280
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Congenital Brucellosis: A Systematic Review of the Literature

Abstract: Brucellosis remains a concern in endemic countries, adversely affecting pregnancy and very rarely causing neonatal infection. Prematurity appeared to be the prime cause of death in neonates with congenital brucellosis.

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Cited by 20 publications
(18 citation statements)
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“…Despite a high burden of infection in many areas of the world, brucellosis is rarely prioritized by health systems and is considered a neglected zoonosis by the World Health Organization (WHO) [3] and World Organisation for Animal Health (OIE) [4]. Brucellosis causes abortion, infertility and milk production decline in animals [5,6]. It is transmitted to humans through consumption of unpasteurized dairy products and uncooked meat or through direct contact with infected animals, placentas or aborted fetuses [7].…”
Section: Introductionmentioning
confidence: 99%
“…Despite a high burden of infection in many areas of the world, brucellosis is rarely prioritized by health systems and is considered a neglected zoonosis by the World Health Organization (WHO) [3] and World Organisation for Animal Health (OIE) [4]. Brucellosis causes abortion, infertility and milk production decline in animals [5,6]. It is transmitted to humans through consumption of unpasteurized dairy products and uncooked meat or through direct contact with infected animals, placentas or aborted fetuses [7].…”
Section: Introductionmentioning
confidence: 99%
“…Human brucellosis is ubiquitous, found in all age groups and both genders likewise [3,5,7] and, consequently, pregnant women can acquire it as well. In the absence of well-designed prospective studies, the current knowledge about brucellosis in pregnant women is based on observational studies and case reports [8]. Therefore, many important questions regarding the incidence of brucellosis in pregnancy, the effect on obstetric outcome and infant health, and vice versa, the influence of pregnancy on the severity and outcome of brucellosis remain unanswered.…”
Section: Introductionmentioning
confidence: 99%
“…However, it is now recognised, with a growing number of epidemiological studies describing increased risks of adverse obstetric outcomes (preterm delivery, spontaneous abortion, fetal death, or low birthweight; Ali et al, ; Alsaif, Dabelah, Featherstone, & Robinson, ; Al‐Tawfiq & Memish, ; Elshamy & Ahmed, ; Giakoumelou et al, ; Gulsun, Aslan, Satici, & Gul, ; Kurdoglu et al, ; Mohammad, El Ghazaly, Zaalouk, Morsy, & El‐Ghazaly, ; Mujuni et al, ; Vilchez, Espinoza, D'Onadio, Saona, & Gotuzzo, ), arguing that brucellosis is a threat for pregnant women. Infection can also be transmitted to the fetus (congenital brucellosis), most probably through transplacental spreading (Alsaif, Dabelah, Girim, Featherstone, & Robinson, ; Aydin et al, ; Giannacopoulos, Eliopoulou, Ziambaras, & Papanastasiou, ; Glocwicz, Stonecipher, & Schulte, ; Koklu et al, ; Mesner et al, ; Poulou, Markou, Xipolitos, & Skandalakis, ; Vilchez et al, ), or to the neonate (neonatal brucellosis), upon exposure to maternal fluids during delivery (Carbajo‐Ferreira, Ochoa‐Sangrador, Canut‐Blasco, & Castaño‐GarcĂ­a, ; Singer et al, ).…”
Section: Introductionmentioning
confidence: 99%