Congenital Complete Atrioventricular Block and Preexcitation Syndrome: A Well-Matched Partner

Abstract

A patient who had been previously diagnosed with congenital complete atrioventricular block (CCAVB) twenty years ago developed atrioventricular (AV) conduction through an accessory pathway (AP). With enhanced sympathetic tone (exercise, isoproterenol), 1:1 conduction down the AP occurred. An electrophysiologic study confirmed a suprahissian AV block and the presence of an AP. The AP was located on the left side and posterior. The absence of retrograde conduction through the AP and also a long conduction time were demonstrated.

Prevalence of neonatal lupus in a small group of antibody-carrying mothers and frequency of complete atrioventricular block

“…Although it is clear that it is not the only factor, these damages include transient intrauterine first-degree heart block, corrected QT interval prolongation, sinus bradycardia, dilated cardiomyopathy, endomyocardial fibroelastosis, hydrops fetalis [17][18][19][20][21][22][23][24] , and some congenital heart diseases 25 , such as atrial and ventricular septal defects, patent ductus arteriosus, coarctation of the aorta, and hypoplastic right ventricle. It has been documented that in the children of mothers carrying anti-Ro and anti-la antibodies, there is a possibility of an increased risk of developing not only CCAB but also Wolff-Parkinson White syndrome [26][27][28][29] . In this study, 100% of the mothers of the cases with NL were carriers of anti-SSA/Ro antibodies (levels > 50 U/mL), and only two were also found to have anti-SSB/La antibodies.…”

A rare coexistence of complete atrioventricular block and preexcitation in an elderly symptomatic patient

“…Why the patient had not developed any symptoms so far remains to be speculated, but one plausible explanation might be a consistent 1 : 1 antegrade conduction through the accessory pathway, whose antegrade refractory period for some reason seems to be remarkably increased with progressive conduction disturbance in the atrioventricular node during the last several weeks causing paroxysmal atrioventricular block. The coexistence of congenital atrioventricular block and ventricular preexcitation, detected usually during early childhood as well as before nonevident preexcitation after His bundle ablation in adults, has been rarely described in isolated case reports [1][2][3][4][5][6][7]. In addition, a clinical study systematically evaluated the relation between the conduction properties of the atrioventricular node and the antegrade conduction ability over the accessory pathway in the Wolff-Parkinson-White (WPW) syndrome.…”