Congenital Epulis in the Newborn, Review of the Literature and a Case Report

Eghbalian, Fatemeh; Monsef, Alireza

doi:10.1097/mph.0b013e31818ab2f7

Cited by 39 publications

(26 citation statements)

References 11 publications

(39 reference statements)

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“…Complications inherent to epulis are related to respiratory function and the act of feeding, which may be greatly affected 10,[14][15][16][17] In the case presented, the person responsible for the baby affirmed that he had difficulty during feeding.…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Congenital epulis with auto-resolution: case report

Siqueira

Carvalho

Monteiro

et al. 2014

RGO, Rev. Gaúch. Odontol.

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Congenital epulis is an uncommon benign lesion that affects the oral cavity of newborns ResumoA epúlide congênita é uma lesão benigna rara que acomete a cavidade oral de recém-nascidos e apresenta características histológicas semelhantes às do tumor de células granulares. A origem da lesão ainda não foi completamente elucidada, e as muitas hipóteses a respeito de sua histogênese baseiam-se na grande variedade de tipos celulares observados nos cortes histológicos. A epúlide desenvolve-se ainda no período pré-natal, e é mais comum em recém-nascidos do sexo feminino, ocorrendo com mais freqüência na maxila. Esta lesão costuma apresentar-se como um nódulo coberto por mucosa oral normal que, em alguns casos, interfere na respiração e na alimentação do bebê. Esse artigo descreve o caso de um bebê do gênero masculino, leucoderma, de dois meses de idade, que apresentava lesão intra-oral pediculada com implantação débil na região alveolar da mandíbula. Cortes histológicos revelaram a presença de fragmento de mucosa revestido por epitélio pavimentoso estratificado atrófico, e de tecido conjuntivo fibroso composto de células com citoplasma granular e eosinofílico abundante. Alguns dias após o exame inicial, a lesão desprendeu-se do rebordo alveolar, sofrendo resolução espontânea.Termos de indexação: Doenças da gengiva. Neoplasias gengivais. Recém-nascido.

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Section: Discussionmentioning

confidence: 99%

“…Solitary lesions are common findings, however, in approximately 10% of cases, multiple lesions are found 1,3,[13][14] . In spite of almost exclusively affecting the alveolar ridge, there are reports involving the dorsum of the tongue in case of multiple epulides 2 .…”

Section: Discussionmentioning

confidence: 99%

Congenital epulis with auto-resolution: case report

Siqueira

Carvalho

Monteiro

et al. 2014

RGO, Rev. Gaúch. Odontol.

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“…Open Journal of Stomatology CE may effect muscles that close the mouth and may prevent swallowing that makes oral feeding impossible. Especially in antenatal period if size of the lesion is large, respiration may be effected and this may cause polyhydromiosis [1] [2] [9]. The diameter of CE varies between 0.1 cm to 4 cm.…”

Section: Discussionmentioning

confidence: 99%

“…Congenital epulis (CE) is also known as congenital granular cell tumor; congenital gingival Neumann's tumor and congenital myoblastoma was firstly defined by Neumann in 1871 [1] [2] [3]. This very rarely encountered soft tissue tumor in newborn is generally located in maxilla [4].…”

Section: Introductionmentioning

confidence: 99%

Congenital Epulis of the Newborn: A Case Report

Pekçetin¹,

Senemtaşı²,

Koçak³

et al. 2018

OJST

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Background: Congenital epulis (CE) also known as congenital granuler cell tumor is a rarely encountered pathology the majority of which originates from the gingival mucosa, particularly the anterior portion of the maxillary alveolar ridge. CE mostly seen in girls. CE with unclear histogenesis and etiology is seen at birth as a solitary mass in oral cavity. Apart from non-congenital epulis, it contains granular cells. So lesion is named congenital granular cell tumor. CE has a benign histopathology and after surgery there is no recurrence reported in the literature. Aim: The purpose of this case report, is to present, 5 day-old female neonatal girl who was seen CE on the left maxillary alveolar ridge on the region of the future incisors. Case Presentation: The tumoral lesion was well-circumscribed and 10 mm in diameter, smooth surfaced and red in colour much like alveolar mucosal tissue. Tumoral lesion was affecting oral feeding due to obstruction. Excisional biopsy was performed under topical anesthesia. The histopathology was reported as congenital epulis. During the 4 months follow-up, we have seen no complication. Conclusion: CE is a neonatal congenital tumor which is very rare. The treatment of CE is surgical excision. Unless the early treatment is not executed, tumor may cause difficulties in oral feeding and respiration. Therefore it should be excised in an early period.

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“…It occurs 2 to 3 times as often on the maxillary alveolar ridge and has a distinctly female predilection (8-10:1). 209,210 The literature is mostly devoted to case reports and attempts at defining the histogenesis through ultrastructural and immunohistochemical means. Most lesions are solitary, usually less than 2 cm, but can be up to several centimeters in size at presentation.…”

Section: Teratomasmentioning

confidence: 99%

Selective Pathologies of the Head and Neck in Children

Ozolek

2009

Advances in Anatomic Pathology

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The range of pathology seen in the head and neck region is truly amazing and to a large extent probably mirrors the complex signaling pathways and careful orchestration of events that occurs between the primordial germ layers during the development of this region. As is true in general for the entire discipline of pediatric pathology, the head and neck pathology within this age group is as diverse and different as its adult counterpart. Cases that come across the pediatric head and neck surgical pathology bench are more heavily weighted toward developmental and congenital lesions such as branchial cleft anomalies, thyroglossal duct cysts, ectopias, heterotopias, choristomas, and primitive tumors. Many congenital "benign" lesions can cause significant morbidity and even mortality if they compress the airway or other vital structures. Exciting investigations into the molecular embryology of craniofacial development have begun to shed light on the pathogenesis of craniofacial developmental lesions and syndromes. Much more investigation is needed, however, to intertwine aberrations in the molecular ontogeny and development of the head and neck regions to the represented pathology. This review will integrate traditional morphologic embryology with some of the recent advances in the molecular pathways of head and neck development followed by a discussion of a variety of developmental lesions finishing with tumors presumed to be derived from pluripotent/progenitor cells and tumors that show anomalous or aborted development.

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Congenital Epulis in the Newborn, Review of the Literature and a Case Report

Cited by 39 publications

References 11 publications

Congenital epulis with auto-resolution: case report

Congenital epulis with auto-resolution: case report

Congenital Epulis of the Newborn: A Case Report

Selective Pathologies of the Head and Neck in Children

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