Congenital Fibrosarcoma of the Upper Extremity

Right foot congenital infantile fibrosarcoma treated only with chemotherapy

“…The clinical course of CIF in children is variable and differs from that of fibrosarcoma in adulthood [14]. Distant metastases are reported in around 8% of pediatric cases [8]. One of the features of the presented case was the destruction of all tarsal, metatarsal, and phalangeal bones; and that the foot would have appeared like a mass-ball had we not discriminated the tips of the toes at the lower part of the mass.…”

“…The extremities are affected in 70% of cases, followed by the trunk, the head, and neck regions [6][7][8]. In addition to these regions, CIF can also originate in the retroperitoneum, colon, abdomen, pelvis, pericardium, or thoracic wall [5,[9][10][11][12][13].…”

Infantile Fibrosarcoma Misdiagnosed as Vascular Tumors

“…MRI is considered to be the technique of choice [3]. In some case reports, both CT and MRI were used and similar findings were reported [2,8,16,17,20,21]. A study was conducted by Canale et al [3] on six patients with IFS where the MRI features were reported to be a large well circumscribed mass, sometimes heterogeneous and septate, and exhibits an isointense T1-and hyperintense T2-weighted signals and strong enhancement with contrast.…”

“…A study was conducted by Canale et al [3] on six patients with IFS where the MRI features were reported to be a large well circumscribed mass, sometimes heterogeneous and septate, and exhibits an isointense T1-and hyperintense T2-weighted signals and strong enhancement with contrast. Other groups report cystic architecture and intralesional bleeding and osseous involvement [1,2,7,8,14,16,17,21,22]. Recurrence and metastasis especially to lymph nodes, bones and lungs, can also be ruled out via imaging, mostly by CT scan [10,14,20].…”

“…Angiography on the other hand is important to check the vascularity of the tumor and the arteries supplying it [1-3, 8, 14, 17, 20]. Angiographic characteristics of IFS include hypervascularity with abnormal caliber and hypertrophied arteries and tortuous and dilated draining veins associated with dense and heterogeneous capillary blush [2,3,8,9,17]. Some of these features may be present in hemangiomas and arterio-venous malformation whereas rapidly involuting capillary hemangioma may exhibit identical angiographic pattern [9] -hence, the confusion with a vascular tumor.…”