Congenital Goiter Found in a District of Omuro, Kochi, Shikoku, Japan

Tezuka, Uichiro; Murakami, Tsuyoshi; Mishiro, Kunio; Fujino, Masaaki; Takeichi, Osamu

doi:10.1507/endocrj1954.18.267

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1971

2007

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Cited by 2 publications

(3 citation statements)

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“…Subsequently, Tezuka et al reported an 8.1% goiter incidence in 482 inhabitants. The goiter was not caused by iodine deficiency; histology and electron microscope findings suggested possible thyroid hormone formation defects [2,3]. Until now, no further studies have been conducted.…”

Section: Dear Sir;mentioning

confidence: 87%

Endemic Goiter due to Thyroglobulin Gene Abnormality and Social Ostracism

et al. 2007

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Section: Dear Sir;mentioning

confidence: 87%

Endemic Goiter due to Thyroglobulin Gene Abnormality and Social Ostracism

et al. 2007

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“…The first possibility was disproved as described in detail in the previous report (Tezuka et al, 1971).…”

Section: Discussionmentioning

confidence: 96%

“…coupling of iodotyrosines to form iodothyronines. In previous papers the authors (Tezuka et al, 1970 and1971) reported that goiters show dominant autosomal heredity of incomplete penetrance in view of their high familial incidence, but there are no reports on the occurrence of this type of goiter, supposedly due to a congenital disorder of iodine metabolism. This paper on the morphology of Omuro goiter describes the pathological changes in ultrastructure of the goiter observed by electron microscopy as well as the result of a gross light microscopic observation.…”

mentioning

confidence: 99%