Congenital infiltrating lipomatosis of the face with hyperplastic mandibular, maxillary and pterygoid bones: case report and a review of literature

Abstract

Congenital infiltrating lipomatosis of the face (CILF) is a rare lipomatous lesion, commonly seen in childhood, and it is characterized by collections of mature, unencapsulated adipose tissues that infiltrate facial soft and hard tissues. The lesion is seen as an overgrowth of bone and soft tissue and is generally present clinically as slow-growing painless masses. In this case report, we described one case of CILF, which is one of the first cases reported in Ghana and Africa as a whole, along with a literature review on the diagnosis and current treatment strategies.

Congenital Infiltrating Lipomatosis of Face-Induced Temporomandibular Joint Ankylosis

“…The spectrum of disorders which should be considered for the differential diagnosis of CILF are lipomas, lipoblastomatosis, lymphatic/vascular malformations, Parry Romberg syndrome, hemifacial microsomia, hemifacial hyperplasia, Launois-Bensaude syndrome, encephalocraniocutaneous lipomatosis, and Proteus syndrome 2,9,10 . Lipoma, a tumor of mature lipocytes comprised of thin fibrous encapsulation which, was ruled out, as in our case, lipid infiltration was diffuse and appeared unencapsulated.…”

“…However, it is associated with various metabolic syndrome components. Both proteus syndrome and encephalocraniocutaneous lipomatosis also display infiltrating lipomatosis as a characteristic feature 10 . However, unlike proteus syndrome, CILF remains confined only to the head and neck region.…”

“…However, unlike proteus syndrome, CILF remains confined only to the head and neck region. Encephalocraniocutaneous lipomatosis is primarily present within the central nervous system, clearly distinguished from CILF 10 …”