Congenital intracranial teratoma

Chien, Yin‐Hsiu; Tsao, Po‐Nien; Lee, Wang-Tso; Peng, Steven Shinn-Forng; Yau, Kuo-Inn Tsou

doi:10.1016/s0887-8994(99)00103-4

Cited by 47 publications

(37 citation statements)

References 8 publications

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“…Anatomical relationships and tissue characteristics are demonstrated by MRI scan with superior detail, except for calcifications (which are better noted with ultrasound and CT scan). As the MRI features of teratomas are relatively nonspecific, the differential diagnosis of congenital supratentorial tumors should also include primitive neuroectodermal tumor, astrocytoma, ependymoma, glioma, craniopharyngioma, and choroid plexus papilloma [12,13].…”

Section: Discussionmentioning

confidence: 99%

A rare case of large fetal intracranial tumor: Teratoma

Gathwal¹,

Kaur²,

Singh³

et al. 2017

IJCRI

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International Journal of Case Reports and Images (IJCRI) is an international, peer reviewed, monthly, open access, online journal, publishing high-quality, articles in all areas of basic medical sciences and clinical specialties.Aim of IJCRI is to encourage the publication of new information by providing a platform for reporting of unique, unusual and rare cases which enhance understanding of disease process, its diagnosis, management and clinico-pathologic correlations.

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Section: Discussionmentioning

confidence: 99%

A rare case of large fetal intracranial tumor: Teratoma

Gathwal¹,

Kaur²,

Singh³

et al. 2017

IJCRI

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“…The prognosis of congenital intracranial teratomas is usually poor with only a 10 % survival rate [5,14,18,19].…”

Section: Resultsmentioning

confidence: 99%

A rare immature teratoma of the tela chorioidea of the third ventricle: late-onset, intrapartum ultrasound diagnosis and postnatal outcome

Tonni¹,

Grisolia

Nanni

et al. 2014

Childs Nerv Syst

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“…24 The exact anatomical location of the tumor cannot be determined in at least one-third of reported cases because so much of the brain is replaced with tumor and identifiable anatomical landmarks are lost. 3,4,10,13,25 In patients for whom the locus of origin can be identified, the cerebral hemispheres are the most common primary site, followed by the third ventricle and pineal region. 9,10 Large tumors may erode through the skull and extend into the orbit, oral cavity, or neck.…”

Section: Discussionmentioning

confidence: 99%

Successful treatment of hemorrhagic congenital intracranial immature teratoma with neoadjuvant chemotherapy and surgery

Fukuoka¹,

Yanagisawa²,

Suzuki³

et al. 2014

PED

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Congenital intracranial immature teratomas carry a dismal prognosis, and the usefulness of chemotherapy for these tumors has not been elucidated. The authors report on the successful management of a case of congenital intracranial immature teratoma by using neoadjuvant chemotherapy and surgery after the failure of an initial attempt at resection. The patient was an infant who had begun vomiting frequently at the age of 12 days and had been admitted to a hospital at the age of 18 days with continued vomiting, increased head circumference, and disturbance of consciousness. A CT scan of the brain revealed a large mass in his posterior fossa and hydrocephalus. Surgery was performed on an emergent basis, but only minor tumor resection could be performed due to massive intraoperative hemorrhage. The histopathological diagnosis was immature teratoma. Postoperatively, the infant was in critical condition due to severe postoperative complications, and when he was transferred to the authors' institution 43 days after birth, his respiratory condition was still unstable because of lower cranial nerve palsy. Chemotherapy with carboplatin and etoposide resulted in moderate shrinkage of the tumor. Further chemotherapy led to improvement in the patient's general condition and weight gain, which allowed for a second attempt at resection. During this second surgery, which was performed when the child was 8 months of age, after 8 courses of chemotherapy, the tumor was completely resected with little bleeding. Histological findings from the second operation were consistent with mature teratoma. This case indicates that upfront chemotherapy may be effective for the initial management of such cases. Although the objective response to the treatment was modest, chemotherapy reduced the hemorrhagic nature of the tumor, facilitated improvement of the patient's general condition, and allowed for successful resection.

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Congenital intracranial teratoma

Cited by 47 publications

References 8 publications

A rare case of large fetal intracranial tumor: Teratoma

A rare case of large fetal intracranial tumor: Teratoma

A rare immature teratoma of the tela chorioidea of the third ventricle: late-onset, intrapartum ultrasound diagnosis and postnatal outcome

Successful treatment of hemorrhagic congenital intracranial immature teratoma with neoadjuvant chemotherapy and surgery

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