Congenital Intraspinal Lipomas: Histological Analysis of 234 Cases and Review of the Literature

Lellouch‐Tubiana, Arielle; Zérah, Michel; Catala, Martin; Brousse, Nicole; Kahn, A.

doi:10.1007/s100249900133

Cited by 44 publications

(36 citation statements)

References 22 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Second is the presence of associated malformations, especially lipomyelocele, lipoma and diastematomyelia [20]. Lipomas of the CM are more underdiagnosed than those of the filum [2,21]. Third is the appearance of the CM.…”

Section: Discussionmentioning

confidence: 99%

Sonographic Evaluation of Fetal Conus Medullaris and Filum Terminale

et al. 2016

Self Cite

View full text Add to dashboard Cite

Background: Sonographic evaluation of the fetal conus medullaris (CM) level is not reproducible. The objectives of this study were to determine the normal position of the fetal CM during pregnancy as well as the normal intradural filum terminale (FT) length and to evaluate their use in detecting tethered cord. Methods: This is a prospective evaluation of normal singleton pregnancies examined by sonography from 17 weeks of gestation to term. Each sonographer had to identify the top of the first sacral vertebra (S1) to measure the distance between it and the conus extremity (CM-S1 distance). The intradural FT distance was measured with 5- to 8-MHz probes. Results: 194 consecutive pregnant women were included. The CM and intradural FT were demonstrated clearly in 164 (84%) cases. The mean CM-S1 distance was 20.6 mm (range 0.5-42). The mean intradural FT distance was 27.9 mm (range 6.6-49.3). Linear regression analysis showed a significant association between both those distances and gestational age (p < 0.05). In cases of tethered cord, the mean CM-S1 distance and the mean intradural FT distance were both below the 5th percentile. Conclusion: Prenatal evaluation of the CM and the intradural FT is feasible and reproducible and seems useful in detecting tethered cord.

show abstract

Section: Discussionmentioning

confidence: 99%

Sonographic Evaluation of Fetal Conus Medullaris and Filum Terminale

et al. 2016

Self Cite

View full text Add to dashboard Cite

show abstract

“…Dass sich bei dieser Patientin zwei intraspinale Lipome an unterschiedlichen Höhen im Rahmen von Diastematomyelien finden, ist ungewöhnlich und findet sich unseres Wissens nicht in der Literatur. Selbst in einer Analyse von 234 intraspinalen Lipomen durch Lellouch-Tubiana et al [7] wird ein mehrmaliges Auftreten von Lipomen nicht berichtet. Lipome sind darüber hinaus vor allem im Rahmen von Lipomyelomenigozelen, aber auch anderen dysraphischen Störungen wie dem Dermalsinus, der Fibrolipomatose, des Filum terminale und dem Split-Notochord-Syndrom vorzufinden [9].…”

Section: Diskussionunclassified

Mehrschicht-Spiral-CT und MRT in der Diagnostik einer komplexen Diastematomyelie

Dammert¹,

Krings²,

Kochs³

et al. 2002

Klinische Neuroradiologie

View full text Add to dashboard Cite

ZusammenfassungHintergrund: Die Diastematomyelie ist zumeist Teil einer komplexen Fehlbildung der Wirbelsäule und ist häufig mit Wirbelkörperanomalien, einer Spina bifida oder einem intraspinalen Lipom assoziiert. Methode: Zur kompletten Charakterisierung der Fehlbildung sollte deshalb neben der MRT als Methode der Wahl die Mehrschicht-Spiral-CT zur überlagerungsfreien Darstellung der knöchernen Strukturen und Festlegung des therapeutischen Procedere eingesetzt werden. Fallbeschreibung: Wir berichten über eine Patientin, die neben multisegmentalen Diastematomyelien und Wirbelkörperfehlbildungen zwei intraspinale Lipome aufwies. Schlüsselwörter: Diastematomyelie · Intraspinales Lipom · MRT · Mehrschicht-CT AbstractBackground: Diastematomyelia is often part of a complex developmental anomaly of the spine and is accompanied by skeletal defects (e.g. spina bifida), other bony anomalies and/or an intraspinal lipoma. Method: Therefore, to fully characterize this lesion and to decide about treatment options, MRI and multi-slice CT should be employed in the diagnostic work up. Case Report: We report on a patient who suffered from diastematomyelia, vertebral body anomalies and two intraspinal lipomas.

show abstract

“…However, lipomas do not consist entirely of fibroadipose tissues. A variety of mesodermal tissues such as bony and cartilaginous tissues, as well as ectodermal and endodermal tissues, are also often observed DOI: 10.1159/000490391 [1,2]. It has been reported that, in 234 histological specimens of spinal lipomas, bone and cartilage was noted in 8 (3%) and 15 (6%), respectively [2].…”

Section: Introductionmentioning

confidence: 99%

Bony and Cartilaginous Tissues in Lumbosacral Lipomas

et al. 2018

View full text Add to dashboard Cite

Purpose: It is well known that bony and cartilaginous tissues can be present in lumbosacral lipomas; however, the relationship between their presence and clinical features has not been demonstrated. Methods: Five (10.4%) out of 48 patients had osteochondral tissues in lipomas. We retrospectively analyzed the clinical, neuroradiological, and histological findings of these patients. Results: Five (45.5%) of 11 patients with dorsal and transitional type lipomas had osteochondral tissues, while none with caudal and filar type lipomas had these tissues. Presurgical imaging demonstrated that the osteochondral tissue was located in a large subcutaneous lipoma dorsal to the bifid vertebral column. Histologically, mature bone with hematopoietic marrow and hyaline cartilage were observed in 3 and 2 patients, respectively. Conclusions: The high incidence of association of osteochondral tissues with dorsal and transitional type lipomas is thought to be the result of primary neurulation failure with invasion of mesenchymal tissues. Caudal and filar type lipomas, resulting from secondary neurulation failure, thus did not have osteochondral tissue.

show abstract

Congenital Intraspinal Lipomas: Histological Analysis of 234 Cases and Review of the Literature

Cited by 44 publications

References 22 publications

Sonographic Evaluation of Fetal Conus Medullaris and Filum Terminale

Sonographic Evaluation of Fetal Conus Medullaris and Filum Terminale

Mehrschicht-Spiral-CT und MRT in der Diagnostik einer komplexen Diastematomyelie

Bony and Cartilaginous Tissues in Lumbosacral Lipomas

Contact Info

Product

Resources

About