Congenital Lipedematous Alopecia: Adding to the Differential Diagnosis of Congenital Alopecia

Lee, Hae-Eul; Kim, Sue-Jeong; Im, Myung; Kim, Chang Deok; Seo, Young‐Joon; Lee, Jeung‐Hoon; Lee, Young Han

doi:10.5021/ad.2015.27.1.87

Cited by 14 publications

(15 citation statements)

References 6 publications

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“…In these patients, there may probably be difficulty in lymphatic flow (7). As in other cases in the literature we could not investigate the lymphatic drainage.…”

Section: Discussionmentioning

confidence: 70%

Çocukta obezite ile birlikte lipoödematöz skalp

Berksoy¹,

Bağ²,

Çelik³

et al. 2016

Ege Tıp Dergisi

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An 11-year-old girl applied for having a spongy consistency of swellings in various part of her scalp. The overlying skin and hair growth of these areas appeared normal. There was no evidence of systemic disease except for exogenous obesity. Ultrasonography showed thickening of the subcutaneous tissue on the swelling part of the scalp. Histopathological examination revealed elastic fibre fragmentation on dermis and increased thickness in the subcutaneous fat tissue containing numerous hair follicles. The clinical features and the histopathological changes in the lesion were consistent with a diagnosis of lipedematous scalp, which has previously been described predominantly in adult women.

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“…In these patients, there may probably be difficulty in lymphatic flow (7). As in other cases in the literature we could not investigate the lymphatic drainage.…”

Section: Discussionmentioning

confidence: 70%

Çocukta obezite ile birlikte lipoödematöz skalp

Berksoy¹,

Bağ²,

Çelik³

et al. 2016

Ege Tıp Dergisi

View full text Add to dashboard Cite

show abstract

“…At first reported in African-American patients, the proposed ethnic predilection seems to be a reporting bias, given the recent published cases of different ethnic origins (Table 2, Table 3). Mostly described in middle-age patients, a few young people, including 2 congenital cases, have also been reported [8, 9]. Family history of the same disease has been reported, which, along with congenital involvement, suggests genetic influences [7, 9, 10].…”

Section: Discussionmentioning

confidence: 97%

“…Mostly described in middle-age patients, a few young people, including 2 congenital cases, have also been reported [8, 9]. Family history of the same disease has been reported, which, along with congenital involvement, suggests genetic influences [7, 9, 10]. Nevertheless, hair styling habits should also be discussed.…”

Section: Discussionmentioning

confidence: 99%

Lipedematous Alopecia: Clinical, Histopathological, and Trichoscopic Findings of a Single Case and Review of the Literature

et al. 2019

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A 66-year-old African woman suffered from a boggy thickening of the scalp in the frontoparietal area and the vertex accompanied by headache since infancy. In her thirties, she developed diffuse hair loss in the same area. Clinical and trichoscopic examination were unhelpful, but the histopathological and radiologic findings led to a diagnosis by demonstrating thick subcutaneous adipose tissue. First described in 1935 by Cornbleet [Arch Dermatol Syphilol. 1935; 32: 688], lipedematous scalp is a rare scalp disease marked by a soft thickening of the scalp. A similar clinicopathologic entity associated with nonscarring but permanent acquired alopecia was described in 1961 by Coskey et al. [Arch Dermatol. 1961 Oct; 84(4): 619–22] and termed lipedematous alopecia. In this article, we report a rare case of lipedematous alopecia with emphasis on a trichoscopic and histopathological description with review of the literature. Our case highlights the importance of palpation during the clinical examination. It remains to be determined whether this is actually a specific disease entity or a combination of 2 separate conditions. Symptomatic treatment is advisable given the lack of robust published data on treatment. Only 40 cases of lipedematous alopecia and 52 cases of lipedematous scalp have been published in the literature. Our case is the 93rd.

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“…[12][13][14][15][16] İnfantil dönemde görülen alopesi nedenlerinin ayırıcı tanısına giren hastalıklar Tablo 1'de görülmektedir. [1][2][3][5][6][7][8][9][10][12][13][14][15][16] Bu olguda SHA hayatın 6. ayından sonra tedricen gelişmiş idi, ancak SHA'lı birçok hastada alopesinin doğumda ya da doğumdan hemen sonra başladığı bildirilmiştir. Bu olguda hayatın genellikle ilk 3 ayında görülen SHA'nın ilk aylarda aile tarafından fark edilememiş olması da dikkat çeki-cidir.…”

Section: Discussionunclassified