Congenital Malformations and Developmental Anomalies of the Lung

Abbey, Pooja; Narula, MK; Anand, Rama

doi:10.1007/s40134-014-0071-y

Cited by 9 publications

(4 citation statements)

References 55 publications

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“…CLMs consist of a continuum of pulmonary development abnormalities that can affect all structures of the respiratory system (lung parenchyma, trachea and bronchi, pulmonary or systemic arteries and veins) as isolated or combined abnormalities, resulting in a large variety of clinical and imaging features. CLMs are generally diagnosed prenatally with ultrasound (US), which is the primary imaging modality for foetal screening [ 3 ] due to its low invasiveness. It provides valuable information about the presence and size of a focal lung lesion [ 11 ], lung hypo-plasia, mass effect, hydrops fetalis, and any other organ malformations, all of which affect the prognosis and mana-gement [ 12 , 13 ].…”

Section: Discussionmentioning

confidence: 99%

“…Other malformations show different degrees of vascular and pulmonary alterations (bronchopulmonary sequestration), and in some abnormalities, including arteriovenous malformation (AVM), there is an altered vascularity with a regular lung parenchyma [ 2 ]. In many cases, radiological features show a combination of multiple malformations, resulting in hybrid lesions [ 3 ].…”

Section: Introductionmentioning

confidence: 99%

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Congenital lung malformations: can we avoid computed tomography? A five-year study

Carfagnini¹,

Vivacqua²,

Baldazzi³

et al. 2023

Pol J Radiol

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Purpose: Congenital lung malformations (CLMs) consist of a variety of pulmonary development disorders. In the CLM approach, computed tomography (CT) is considered the gold standard imaging technique due to the high-resolution for the lung parenchyma evaluation, the study of the vascular system after contrast injection, and the multiplanar reconstructions. In the paediatric population CT is considered too invasive due to ionizing radiation and the use of contrast agent. Therefore, the indications for the use of magnetic resonance imaging (MRI) are increasing. The aim of our study is to compare retrospectively MRI and CT in the evaluation of CLMs, to reduce or avoid the use of contrast-enhanced CT in the paediatric population. Material and methods:We retrospectively evaluated 22 paediatric patients with prenatal diagnosis of CLMs. All the patients underwent postnatal MRI in the first 2 weeks of life (except for a patient) and pre-surgery contrast-enhanced CT. A total of 7 blinded radiologists divided into 3 different groups independently reviewed each MRI and CT examination. Sensitivity and specificity of radiologists with different years of experience on the field, as well as of MRI findings regarding every pathology, were evaluated using a ROC curve. The interobserver agreement regarding the MRI findings was also measured. Results:Analysing the ROC curves, we observed that MRI provided a satisfactory accuracy for diagnosing most congenital pulmonary diseases. Conclusions:Our study showed that MRI without contrast agent allows us to reach a CLM diagnosis in good agreement with contrast-enhanced CT, which is considered the gold standard imaging technique.

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Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Congenital lung malformations: can we avoid computed tomography? A five-year study

Carfagnini¹,

Vivacqua²,

Baldazzi³

et al. 2023

Pol J Radiol

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“…Pulmonary agenesis is a rare malformation usually seen alone or in association with other anomalies [2]. The exact incidence and prevalence of lung agenesis are also unknown; however, recent literature has quoted an estimated incidence of 1.22 per 100,000 new births [3].…”

Section: Discussionmentioning

confidence: 99%

Scoliosis correction surgery in a patient with unilateral pulmonary agenesis: A case report and review of literature

Khabir,

Wang,

Pan

et al. 2023

Open J Clin Med Case Rep

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Secondary scoliosis is caused by diseases wherein there is a lack of support for the spine, resulting in unequal pressures on the sides of the spinal cord. Secondary scoliosis is usually due to a neuromuscular disorder such as cerebral palsy, poliomyelitis, spina bifida, or a muscular dystrophy and is rarely secondary to pulmonary abnormalities. In this paper, we will specifically focus on the spine deformities associated with pulmonary diseases. We report a case of an adolescent female presenting with shoulder imbalance and marked scoliosis with a history of pulmonary agenesis. The patient underwent scoliosis correction surgery with instrumentation and fusion. Postoperatively, the patient showed improvement in the Cobb angle as well as marked improvement in her respiratory function. This review may raise awareness of the association between severe scoliosis and childhood lung absence and stimulate further prospective research efforts.

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“…The furrows become progressively deeper and eventually join with the craniad, thereby separating the ventral laryngotracheal tube from the dorsal esophagus 5 . To date, there are four main theories for the development of a congenital trachea and pulmonary malformations 6,7 : (1) defective foregut budding, differentiation, and separation; (2) airway obstruction; (3) vascular abnormality; and (4) genetic causes. These proposed mechanisms may act alone or in combination.…”

Section: Discussionmentioning

confidence: 99%

Prenatal diagnosis of pulmonary artery sling associated with tracheal agenesis: A case report

Huo

et al. 2020

Echocardiography

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Pulmonary artery sling (PAS) and tracheal agenesis (TA) are rare diseases, and most cases of PAS are associated with tracheal bronchial malformations. However, PAS associated with TA is yet to be reported. We report a case of PAS with TA diagnosed prenatally. Due to the extremely low incidence, physicians do not have sufficient understanding of these diseases and it is challenging to diagnose these diseases by prenatal ultrasound, with high rates of misdiagnosis. Prenatal examination of the pulmonary artery branches, trachea, and esophagus is useful; therefore, improving the accuracy of prenatal diagnosis will help in perinatal management and counseling.

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Congenital Malformations and Developmental Anomalies of the Lung

Cited by 9 publications

References 55 publications

Congenital lung malformations: can we avoid computed tomography? A five-year study

Congenital lung malformations: can we avoid computed tomography? A five-year study

Scoliosis correction surgery in a patient with unilateral pulmonary agenesis: A case report and review of literature

Prenatal diagnosis of pulmonary artery sling associated with tracheal agenesis: A case report

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