Congenital malformations in Assam

Dutta, Hemonta Kumar; Nc, Bhattacharyya; Sarma, JN; Kusre, Giriraj

doi:10.4103/0971-9261.70639

Cited by 21 publications

(23 citation statements)

References 7 publications

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“…Birth defects comprised about 45% of all pediatric surgical admissions. We found a higher occurrence of birth defects in males than females, a finding that is in contrast to another study in Iran who reported no sex difference 12 . Birth defects occurred twice in male than in female.…”

Section: Discussioncontrasting

confidence: 56%

Birth Defects: A Hospital Based Study in Chittagong, Bangladesh

Banu

Chowdhury

Das

et al. 2014

Chatt Maa Shi Hosp Med Coll J

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Introduction: Birth defects are one of the most common causes of disability in developed and developing countries. Birth defects are structural or functional anomalies, including metabolic disorders, which are present at the time of birth. Although the worldwide incidence of birth defects is estimated at 3-7%, the rate varies widely between countries. In this paper, we categorized the birth defects most commonly seen in Bangladesh and their outcome. We hope to use this information to guide the strategies used to manage these problems. Materials and Methods: This hospital based, descriptive study was done in the Department of Pediatric Surgery in Chittagong Medical College and Hospital from January 2008 to December 2012. Records of all patients with birth defects in our hospital and departmental database were reviewed. Types of birth defects, age, sex, surgery performed and outcome were analyzed in patients admitted during this period. Data were analyzed by SPSS 17. Statistical analysis was performed by the chi-square test and mean and percentage values were calculated. P<0.05 was considered to be statistically significant. Results: During this five year period, there were 5661 patients of birth defects admitted in this department. Of these, 5156 had a single congenital anomaly and 505 had multiple congenital anomalies. The male to female ratio was 2.1: 1. Birth defects comprised 44.61% of all Pediatric surgical admissions and 0.90% of total hospital admissions. The gastrointestinal system was the most common organ system involved, followed by the genitourinary system. Inguinal hernias were the most common gastrointestinal abnormality and hypospadias were the most common genitourinary case. A total of 3921 operations were performed for birth defects, representing 69.26% of total admission for birth defects. Most operations were done for gastrointestinal and genito-urinary defects. Inguinal herniotomy was the most commonly performed operation followed by laparotomy for various indications. There were 225 deaths for birth defects. While this is only 3.97% of all admissions for birth defects, this represents 51.49% of all (pediatric) deaths during the study period. The most common cause of death was anorectal malformations followed by gastroschisis. Conclusion: The study helps assess the burden of birth defects in the Bangladeshi society. There is a need for more extensive, nationwide screening studies to determine the birth prevalence, types and distribution of birth defects in Bangladesh.

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Section: Discussioncontrasting

confidence: 56%

Birth Defects: A Hospital Based Study in Chittagong, Bangladesh

Banu

Chowdhury

Das

et al. 2014

Chatt Maa Shi Hosp Med Coll J

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“…The incidence of genitourinary anomalies was 16.7% in our study, which is less than study done by Dutta et al 22 Multiple anomalies were present in 15%, which is greater than the incidence reported by Hasan et al 3 2010 (6.6%).…”

Section: Discussioncontrasting

confidence: 72%

Incidence of Congenital Anomalies in Tertiary Health Care Centre

Naseha¹,

Iqbal²

2016

jemds

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BACKGROUNDCongenital fetal anomalies have been the concern of obstetricians and society for many centuries. A congenital fetal abnormality often results in spontaneous abortion or perinatal death, commonly associated with prematurity or major handicap including mental retardation. The study of congenital anomalies is of utmost importance in reducing the number of perinatal deaths. Understanding the aetiological factors in the causation of congenital malformation helps in prevention. Pregnancy with fetal lethal abnormalities can be terminated.

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“…6,7 53.2% of babies with malformations weighed less than <2500 gm in the present study. Similar observation (59.8% in babies <2500gm) has been seen in study by Patel ZM.…”

Section: Discussionmentioning

confidence: 42%

Prevalence, pattern and outcome of congenital malformations in a tertiary care centre in South India

Neelambari¹,

Das²,

Srinivasan³

et al. 2018

Int J Contemp Pediatr

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Background: Congenital malformations are of major concern as they are cosmetically unacceptable, often associated with significant functional abnormalities and may sometimes even be life-threatening. This study was done to explore the prevalence of structural congenital malformation among hospital newborns, both live and stillborn in a tertiary care center in Southern India.Methods: This hospital-based prospective study involving all inborn neonates and still births was conducted for the period from January 2014 to December 2014. A total of 2276 newborn (2217 live births and 59 still births) were clinically examined for detection of gross congenital malformations and relevant investigations including karyotyping was done. Risk factors that had probable associations with birth defects were estimated by calculating the Odd’s Ratio. Statistical analysis was done using Chi-Square test.Results: The prevalence of congenital malformations was 12%. Major malformations accounted for 53.28% and minor malformations 46.71%. The commonest structural malformation involved cardiovascular system. 58% of neonates did not require life style medications whereas 21.17% required surgical intervention. 20.8% of the cases succumbed to death.Conclusions: Autopsy of stillborn babies should be done to evaluate the cause and incidence of malformations. High risk mothers should be identified in the antenatal period to detect malformations early and plan management accordingly.

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Congenital malformations in Assam

Cited by 21 publications

References 7 publications

Birth Defects: A Hospital Based Study in Chittagong, Bangladesh

Birth Defects: A Hospital Based Study in Chittagong, Bangladesh

Incidence of Congenital Anomalies in Tertiary Health Care Centre

Prevalence, pattern and outcome of congenital malformations in a tertiary care centre in South India

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