Congenital masses of the lung: Changes in cross-sectional area during gestation

Neonatal outcome of antenatally diagnosed congenital cystic adenomatoid malformations

“…Previous studies reporting on prenatally detected CCAMs have produced highly variable estimates of perinatal mortality from 9% to 49%1–9. Reliable data on the prognosis and postnatal outcome of CCAMs are limited because previous studies were conducted on either small or highly selected populations4–6, 10–13. The trend of survival data has shown a consistent improvement with more recent publications with perinatal mortality rates of 49% in 1992 ( n = 58)9, 22% in 1995 ( n = 77)12 to 9% in 2001 ( n = 54)1.…”

Large fetal congenital cystic adenomatoid malformations: growth trends and patient survival

“…Thus, fetuses can often boutgrowQ their lesions if they can survive into the early third trimester while averting hydrops. This growth phenomenon was originally proposed almost a decade ago [17]. Unfortunately, the concept has been difficult to validate because previous studies have relied exclusively on cross-sectional measurements obtained on ultrasound.…”

“…Unfortunately, the concept has been difficult to validate because previous studies have relied exclusively on cross-sectional measurements obtained on ultrasound. The problems associated with sonographic measurements in quantifying volume changes over time are well known [17]. Because of fetal positioning, there is an inherent variability in obtaining serial measurements along the exact same plane.…”

Bronchopulmonary foregut malformations: embryology, radiology and quandary

“…A small study by Winters et al measured cross-sectional area of eight masses with features of CCAM types 1-3 and found a favourable outcome in those fetuses where thoracic growth exceeded that of the mass [49]. The apparent decrease in size of lesions could be secondary to a change in the fluid/ tissue interface so that the mass becomes isoechoic with normal lung [4].…”