Congenital multiple pituitary hormone deficiency associated with hyperammonemia: a case report with a short review of the literature

Abstract

We herein report a case study of a female newborn with multiple pituitary hormone deficiencies who presented with generalized seizures, hypoglycemia and hyperammonemia at 18 h after birth. In addition, we review the association of hyperammonemia in neonates with multiple pituitary hormone deficiencies reported in the previous literature. This unrecognized association should be taken into account for the early diagnosis and treatment of these patients.

Congenital Hypopituitarismin Saudi Arabia: Is it That Rare?

“…Onset can be at any time of life, it might be lethal if not diagnosed and treated early. It is reported in association with other diseases like Shaw Ashman-Diamond syndrome, hyperemia and slipped capital femoral epiphysis [12][13][14]. Jain et al [15] reported the adverse on the heart.…”