Congenital Partial Hemihypertrophy Involving Marked Malocclusion

A Rare Case of Hemifacial Hypertrophy- Orthodontic Perspective

“…The disorder occurs more commonly in females as compared to males with ratio of 3:2. Right side of the face is more commonly affected [5] than the left.…”

Hemihypertrophy Spectrum

“…Barsky [24] and others found no report of familial occurrence. On the other hand, there have been many reports of familial hemihyperplasia in the literature with two or more affected relatives [24][25][26][27][28][29][30][31][32]. However, some of these patients had additional features, suggesting that not all of the families had IH [27].…”

“…Lacombe and Battin [26] described 2 children diagnosed at birth as isolated megalodactyly. Their follow-up examination showed development of hemihypertrophy and other findings suggesting Proteus syndrome [9].…”

Hemifacial hypertrophy: Exploring new avenues of treatment modalities

“…[12] No single theory explains the etiology adequately. The professed causes for this condition include inherited chromosomal abnormalities[1314] endocrine dysfunctions, vascular or lymphatic malformation, atypical forms of twinning, altered intrauterine environment, and disturbances of the central nervous system[1516] Pollock et al . [17] advocated that an enlarged neural tube on one side is responsible for the unilateral increase in size.…”