Congenital presentation of a solitary superficial angiomyxoma in the parotid region masquerading as parotid tumor

Abstract

Superficial angiomyxoma is a rare cutaneous and benign lesion. We present a case of congenital presentation of a superficial angiomyxoma in the parotid region in a 9-year-old female that was misdiagnosed as a parotid tumor. Appropriate diagnosis is important since such lesions have a good prognosis and rarely affect deeper structures. Possibility of superficial angiomyxoma should be kept in mind in the differential diagnosis of lesions of the parotid region.

Solitary superficial angiomyxoma of the ear pinna: a diagnostic dilemma with a review of literature

“…In order to distinguish it from aggressive angiomyxoma, the term superficial angiomyxoma was employed. Aggressive angiomyxomas differ from superficial angiomyxomas by appearing in deeper sites and as bigger nodules in the genital, pelvic, and perineal regions [ 10 ]. Patients with superficial angiomyxoma typically have asymptomatic pink-colored, fleshy lesions that tend to appear on the neck, head, and lower limbs.…”

Pediatric Vulvar Superficial Angiomyxoma: A Case Report With Clinical, Radiological, and Anatomopathological Characterization and a Comprehensive Review of the Literature

“…Superficial angiomyxoma is an extremely infrequent tumor in the pediatric population, with only 22 cases reported to date in the English scientific literature (including ours). 4,5,[9][10][11][12][13][14][15][16][17][18][19][20][21] A comprehensive review of the published cases and their clinical, radiological, and pathological features is shown in Table 1.…”

“…The same is true for desmin. 17,19,21 On the other hand, only one study reports immunohistochemistry for the estrogen and progesterone receptors, 10 which was negative. In our case, the characterization is consistent with these findings (with negative desmin and with focal positivity for actin), bringing as a novelty finding negativity for myogenin and Myo-D1.…”

“…In relation to the histopathological characterization of this lesion, the literature is consistent, with multiple papers characterizing the lesion immunohistochemically as S100 (−), vimentin (+), keratin (+), and CD34 (+). Smooth muscle actin alpha has been reported to be both positive 17,21 and negative 11 depending on the series. The same is true for desmin.…”