Congenital Psoriasis Following the Lines of Blaschko

Lehners‐Weber, Christiane; Brassinne, Michel De La; Dezfoulian, Bita; Richert, Bertrand; Bonardeaux, Chantal; Willemaers, Valentine

doi:10.1111/j.1525-1470.1996.tb01206.x

Cited by 16 publications

(3 citation statements)

References 10 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Saraswat et al [7] described the clinical differences between the two entities. A late onset of asymptomatic to slightly itchy lesions with a possible involvement of scalp and nails and a favorable response to antipsoriatic treatment favors the diagnosis of linear psoriasis [8, 9]. In contrast, ILVEN lesions usually occur in the first months of life, are slowly progressive, very pruritic and highly refractory to antipsoriatic therapy.…”

Section: Discussionmentioning

confidence: 99%

Linear Psoriasis – A Case Report

et al. 2011

View full text Add to dashboard Cite

A 56-year-old woman presented with a 3-month history of erythematous plaques covered by scales and limited to the right side of her body. The plaques were arranged along Blaschko’s lines with a marked mid-line cutoff. The histopathologic analysis of a skin biopsy in conjunction with the anamnesis allowed the diagnosis of linear psoriasis. Our patient showed a good clinical response to antipsoriatic treatment.

show abstract

Section: Discussionmentioning

confidence: 99%

Linear Psoriasis – A Case Report

et al. 2011

View full text Add to dashboard Cite

show abstract

“…1 a, b). These lines evoke the migration of embryonic cells, causing them to proliferate anterolaterally from the neural crest [ 10 ].…”

Section: Discussionmentioning

confidence: 99%

Clinical Characteristics and Therapeutic Aspects of Blaschko Linear Psoriasis

Chen,

Cheng,

Peng

et al. 2024

Dermatol Ther (Heidelb)

View full text Add to dashboard Cite

Introduction Blaschko linear psoriasis (BLP) is characterized by the linear distribution of psoriatic skin lesions along the Blaschko lines. BLP can be divided into type I and type II, mainly on the basis of clinical manifestations. BLP can easily cause psychological burdens in patients and clinical confusion for physicians. Here, we summarize clinical cases to provide a better understanding of BLP. Methods The subjects included patients with BLP who visited our dermatology departments and those reported in the literature obtained from the PubMed and Wanfang databases. Quantitative data were presented as means ± SD (standard deviation), and qualitative data were represented by the frequency. Student’s t test was employed to compare means, whereas chi-square tests were used for analyzing qualitative data. Results A total of 74 patients with BLP (5 our patients, 69 from literature) were included, with 61 type I and 13 type II patients. We summarize BLP’s characteristics as follows: (1) More frequent in male individuals, especially in type II; (2) Earlier onset than classical psoriasis; (3) Mainly distributed unilaterally, and no preference for left or right site; (4) Asymptomatic or slight pruritus; (5) Mostly negative family history of psoriasis; (6) Possible involvement of the nails/scalp (mainly for type II); (7) Possible exogenous triggering or aggravation factors; (8) Possible concomitant classical plaque or guttate psoriasis lesions, especially in type II; (9) Conforming to histopathology features of classical psoriasis; (10) Relatively favorable response to antipsoriatic treatment, although poor for superimposed areas in type II. Conclusion This study analyzed the clinical characteristics and therapeutic aspects of BLP. Compared with published studies, we have new findings, such as gender bias. Besides traditional antipsoriatic treatment, a personalized selection of biologics may also be a promising choice. Dermatologists should recognize and understand the significance of this disease, and provide patients with appropriate psychological counseling and clinical treatments. Supplementary Information The online version contains supplementary material available at 10.1007/s13555-024-01140-0.

show abstract

“…[1][2][3][4][5] The term 'congenital Blaschkoid psoriasis' was suggested for its lesions following the lines of Blaschko. 1 Al-Fouzan et al 2 described a girl with two localized psoriatic plaques at birth, who subsequently developed generalized scaly plaques in linear bands and streaks. Multiple linear bands of naevoid psoriasis along Blaschko's lines have also been reported.…”

Section: Discussionmentioning

confidence: 99%