Congenital sialoblastoma: A case report and review of literature

Aggarwal, Riti; Bhalla, Sunita; Chopra, Prem; Kulshreshtha, Rajeev

doi:10.4103/0975-8844.124261

Cited by 3 publications

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“…In the screening phase, 103 articles were selected for full‐text evaluation. Of these, 51 selected studies 3,5,7–10,13–57 met the eligibility criteria. Additionally, 1 article 58 was added from a manual search of the reference lists of included studies, resulting in the inclusion of 52 articles in the qualitative synthesis.…”

Section: Resultsmentioning

confidence: 99%

Clinicopathological study and survival outcomes of sialoblastoma: A systematic review

et al. 2023

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Sialoblastoma is a rare malignant salivary gland tumor. The aim of this study was to review the available published data on sialoblastoma in a comprehensive analysis of its clinicopathologic characteristics, treatment, and outcomes. An unrestricted electronic search was performed in the following databases: MEDLINE/PubMed, EMBASE, Scopus, Web of science, and gray literature databases. Eligibility criteria included publications with sufficient clinical, imaging, and histopathological information to confirm the diagnosis of sialoblastoma. Data were evaluated descriptively and analytically. A total of 52 studies met the eligibility criteria. In total, 62 patients were evaluated. There was no gender predilection, with the parotid being the most affected primary site (n = 28; 45.2%). In the log‐rank test, there was a significant increase in disease‐associated survival in patients younger than 1 year of age (82.8% vs. 44.4%; p = 0.003), individuals with lesions in major salivary glands (79.4% vs. 38.5%; p = 0.005), patients without metastases (77.8% vs. 14.3%; p = 0.011), encapsulated lesions (85.7% vs. 0%; p < 0.0001), congenital lesions (83.3% vs. 25.0%; p < 0.0001), and lesions that do not show perineural invasion (89.5% vs. 40%; p = 0.035). Kaplan–Meier curves estimated overall survival and disease‐free survival at 5 years of 95.5% and 68.1%, respectively. In the multivariate Cox regression model, only the presence of metastasis was identified as an independent prognostic factor (hazard ratio [HR] = 9.81; p = 0.010). Although sialoblastoma presents good prognosis, the tumor has a high recurrence rate.

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Section: Resultsmentioning

confidence: 99%

Clinicopathological study and survival outcomes of sialoblastoma: A systematic review

et al. 2023

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“…In our case, the perineural invasion predicted the invasive character and the unfavorable prognosis the tumor (Figure ). However, the biological behavior of these tumors can only be predicted with long‐term follow‐up …”

Section: Discussionmentioning

confidence: 99%

Sialoblastoma of the parotid gland in a 13‐year‐old girl with multiple recurrences and long‐term follow‐up

2015

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Malignant mixed tumour of the parotid gland in a preterm neonate with cytomegalovirus infection

et al. 2022

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A young pregnant woman presented to the emergency department with acute lower abdominal pain. The ultrasound examination showed not only a viable fetus with a gestational age of 24 weeks but also a heteroechoic mass of about 7×7 cm involving parts of the face. The patient was found to be in active labour with rapid progression, and she gave birth to a dead female neonate. The autopsy showed a large malignant mixed tumour of the left parotid gland and revealed infection with cytomegalovirus. To our knowledge, this is the first reported case of a malignant mixed tumour of salivary glands in fetuses.

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Congenital sialoblastoma: A case report and review of literature

Cited by 3 publications

References 0 publications

Clinicopathological study and survival outcomes of sialoblastoma: A systematic review

Clinicopathological study and survival outcomes of sialoblastoma: A systematic review

Sialoblastoma of the parotid gland in a 13‐year‐old girl with multiple recurrences and long‐term follow‐up

Malignant mixed tumour of the parotid gland in a preterm neonate with cytomegalovirus infection

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