Congenital supravalvular aortic stenosis in a kitten

Szatmári, Viktor

doi:10.1016/j.jvc.2022.04.001

Cited by 1 publication

(2 citation statements)

References 7 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The systolic anterior motion of the mitral valve (SAM) is defined as the systolic displacement of the septal mitral valve leaflet into the left ventricular outflow tract (LVOT), causing mitral valve regurgitation and dynamic left ventricular outflow tract obstruction (DLVOTO) [ 1 ]. Systolic anterior motion can be caused by left ventricular concentric hypertrophy (cLVH) of any cause or by a primary congenital disorder of the mitral valve apparatus [ 2 , 3 , 4 , 5 , 6 , 7 ].…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Prevalence and Prognosis of Atenolol-Responsive Systolic Anterior Motion of the Septal Mitral Valve Leaflet in Young Cats with Severe Dynamic Left Ventricular Outflow Tract Obstruction

Kortas

Szatmári

2022

Animals

View full text Add to dashboard Cite

Background: Severe dynamic left ventricular outflow tract obstruction (DLVOTO) secondary to the systolic anterior motion of the septal mitral valve leaflet (SAM) can result either from congenital mitral valve disorders or left ventricular concentric hypertrophy of any cause, in cats commonly hypertrophic cardiomyopathy (HCM). Though HCM cannot be reversed, the question remains whether atenolol can cure cats with severe DLVOTO resulting from a presumed mitral valve dysplasia. Methods: In this retrospective case series, client-owned asymptomatic cats younger than 1.5 years with echocardiographic evidence of SAM and severe DLVOTO were included. Oral atenolol therapy and recheck echocardiography after 2–3 months were recommended. The owners and referring veterinarians were called for long-term follow-up information. Results: Of the 28 included cats, 23 were treated with atenolol. Recheck echocardiography performed in 17 cats showed a resolution of SAM in 47%. In the long term, SAM remained absent in only 9% of the treated cats. Cardiac-related death occurred in 26% of the atenolol-treated cats. Conclusions: The long term benefit of twice-daily atenolol therapy was documented in 9% of cats. Whether the cats where atenolol failed to resolve DLVOTO on long-term had HCM, or a therapy-resistant congenital primary mitral valve disorder remains unclear.

show abstract

Section: Introductionmentioning

confidence: 99%

“…Oral atenolol therapy might resolve SAM by its negative inotropic effect in some cats and in young dogs with severe DLVOTO [ 5 , 6 , 7 ]. If the DLVOTO is resolved or its severity is decreased, the cLVH will resolve or decrease too (reverse remodeling), in case it was caused by chronic pressure overload.…”

Section: Introductionmentioning

confidence: 99%

Prevalence and Prognosis of Atenolol-Responsive Systolic Anterior Motion of the Septal Mitral Valve Leaflet in Young Cats with Severe Dynamic Left Ventricular Outflow Tract Obstruction

Kortas

Szatmári

2022

Animals

View full text Add to dashboard Cite

show abstract

Congenital supravalvular aortic stenosis in a kitten

Cited by 1 publication

References 7 publications

Prevalence and Prognosis of Atenolol-Responsive Systolic Anterior Motion of the Septal Mitral Valve Leaflet in Young Cats with Severe Dynamic Left Ventricular Outflow Tract Obstruction

Prevalence and Prognosis of Atenolol-Responsive Systolic Anterior Motion of the Septal Mitral Valve Leaflet in Young Cats with Severe Dynamic Left Ventricular Outflow Tract Obstruction

Contact Info

Product

Resources

About