Congenitally Absent Permanent Teeth Among Mongols and Their Sibs*

Orner, G.

doi:10.1111/j.1365-2788.1971.tb01168.x

Cited by 7 publications

(17 citation statements)

References 9 publications

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“…Most studies report that mandibular second premolars, maxillary lateral incisors, maxillary second premolars, and mandibular central incisors are the teeth most often affected (in decreasing order). 35 In DS, the prevalence of hypodontia is much greater and more severe [12][13][14][15][16][17][18][19][20][21][22] and is recognized as a characteristic phenotypical feature of the syndrome.…”

Section: Discussionmentioning

confidence: 99%

“…Similarly, measurements of subjects exhibiting absence of all third molars were compared with those without this presentation. Since dental agenesis is frequently observed in both jaws in DS, [12][13][14][15][16][17][18][19][20][21][22] ANCOVA tests were additionally adjusted for the proportion of other missing teeth (vs in the regions of interest) in the total number of missing teeth. Statistical tests were conducted using SAS (version 9.1; SAS Institute Inc, Cary, NC).…”

Section: Methodsmentioning

confidence: 99%

“…2 Cephalometric analyses of subjects with DS have described platybasia, reduced maxillary and mandibular alveolar heights, short teeth, reduced maxillary and mandibular dimensions, and forward rotation of the maxillary and mandibular planes, which collectively lead to overclosure and relative mandibular prognathism. [3][4][5][6][7][8][9][10][11][12] Hypodontia in DS is well known, [12][13][14][15][16][17][18][19][20][21][22] with prevalence documented at about 90% 12,19,20 if the third molars are considered and between 30% 13 and 60% 22 when the third molars are not considered in the analysis. A very high prevalence of total agenesis of all third molars has also been described.…”

Section: Introductionmentioning

confidence: 99%

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Prevalence and patterns of permanent tooth agenesis in Down syndrome and their association with craniofacial morphology

Suri¹,

Tompson²,

Atenafu³

2011

The Angle Orthodontist

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Objective: To (1) document the prevalence and patterns of hypodontia (permanent tooth agenesis) in Down syndrome (DS) and (2) explore whether maxillary or mandibular hypodontia or simultaneous agenesis of all third molars was associated with differential alterations of the craniofacial morphology. Materials and Methods: Longitudinal panoramic radiographs of 25 white patients with DS (12 male, 13 female; mean age, 15.1 years) treated at The Hospital for Sick Children, Toronto, Ontario, Canada, were evaluated to document hypodontia. Cephalometric measurements of subjects with maxillary or mandibular hypodontia or agenesis of all third molars were compared with those of subjects without hypodontia in these regions using analysis of covariance adjusted for age, gender, and proportion of other missing teeth in the total number of missing teeth. Results: Hypodontia was seen in 92% of the sample when third molars were considered and in 56% when third molars were not considered. Hypodontia was more prevalent and severe in females. The most frequently agenetic teeth were maxillary and mandibular third molars . maxillary lateral incisors . mandibular second premolars . mandibular incisors . maxillary second premolars . maxillary second molars. Simultaneous agenesis of all third molars was seen in 52% of the sample. Maxillary hypodontia was not associated with significant regional craniofacial differences, while mandibular hypodontia was associated with decreased mandibular length and increased ramus:body ratio. Agenesis of all third molars was not associated with significant craniofacial differences. Conclusions: Hypodontia is widely prevalent in DS. The effect of the syndrome appears to be stronger than that of regional hypodontia in differentially altering the craniofacial morphology. (Angle Orthod. 2011;81:260-269.)

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Section: Discussionmentioning

confidence: 99%

Section: Methodsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Prevalence and patterns of permanent tooth agenesis in Down syndrome and their association with craniofacial morphology

Suri¹,

Tompson²,

Atenafu³

2011

The Angle Orthodontist

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“…The most frequent absent teeth were lower incisors, followed by upper second premolars, upper lateral incisors, lower second premolars, upper second molars, lower central incisors and canines. As from an earlier U.S. study (Orner, 1971), the author reported that 53% out of 212 DS individuals had missing permanent teeth. The descending frequency of missing teeth were the upper lateral incisors (31%) followed by the lower second premolars (26%), upper second premolars (18%), lower lateral incisors (12%), and lower central incisors (7%).…”

Section: Hypodontiamentioning

confidence: 52%

Oral Health in Individuals with Down Syndrome

Cheng¹,

Yiu²,

Leung³

2011

Prenatal Diagnosis and Screening for Down Syndrome

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“…Many dental anomalies in subjects with Down syndrome (DS; trisomy 21) have been reported worldwide. Abnormalities in number (hypodontia), size (smaller), morphology (peg shaped), and late development of their dentition are often observed . The prevalence of agenesis (usually bilateral) of permanent teeth (excluding the third molars) has been reported to be higher in children with DS than in normal children; the results given vary from 30% to 60% .…”

Section: Introductionmentioning

confidence: 99%

Distribution of permanent canine agenesis in Down syndrome: 15 cases from a Centre for Special Care Dentistry

Reuland-Bosma

Reuland

Bronkhorst

2014

Special Care in Dentistry

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The purpose of this study was to investigate the distribution of permanent canine agenesis in subjects with Down syndrome (DS). Subjects with canine agenesis were determined by means of panoramic radiographs from 150 DS subjects attending a center for special care dentistry. Our results confirm the high prevalence of agenetic canines in DS (21 canines, 14%). We found specific effects on the distribution both of phenotype and of location (jaw). In subjects with a mild expression of hypodontia (phenotype nonoligodontia) agenetic canines primarily occurred in the mandibula, whereas in subjects with severe hypodontia (phenotype oligodontia) agenetic canines virtually only occurred in the maxilla. In both phenotypes cooccurrence of an agenetic lateral incisor with an agenetic canine was observed in the maxilla. It was striking that canine agenesis in the mandibula did not cooccur with agenesis of other teeth. These results can be important for treatment planning.

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Congenitally Absent Permanent Teeth Among Mongols and Their Sibs*

Cited by 7 publications

References 9 publications

Prevalence and patterns of permanent tooth agenesis in Down syndrome and their association with craniofacial morphology

Prevalence and patterns of permanent tooth agenesis in Down syndrome and their association with craniofacial morphology

Oral Health in Individuals with Down Syndrome

Distribution of permanent canine agenesis in Down syndrome: 15 cases from a Centre for Special Care Dentistry

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