Congestive cardiomyopathy in uraemic patients on long term haemodialysis.

Abstract

cause. It would be interesting to know how many of the perinatal deaths in the "anoxic" group in Cardiff corresponded to deaths of unknown cause in mature infants and to know the age, parity, height, and social class of the mothers. Higher induction and section rates in these groups most at risk might have resulted in better figures.Fedrick and Yudkin9 reported a reduction in the number of stillbirths in the Oxford area associated with a rising induction rate. The reduction was more apparent in induced than in noninduced births. As they pointed out themselves, however, when the induction rate is low only pregnancies at very great risk are included in an induced group, but as the induction rate rises, more and more relatively normal cases are induced. It is difficult, therefore, to draw firm conclusions about the benefits of induced labour from their method of analysing their data. Possibly the optimum induction rate will vary from area to area depending on the characteristics of the populations. By detailed analysis of our population and classification of the causes of our perinatal deaths, we were able to show where greatest improvement could be made, and it would be valuable to compare our results with those from other centres. Our present findings strongly suggest that increased use of induction of labour has contributed to a reduction in perinatal mortality.

Origins of Cardiorenal Syndrome and the Cardiorenal Connection

“…[29][30][31][32] The full extent of the problem of cardiovascular disease in chronic kidney disease (CKD) and ESRD patients was then charted in the 1990's, showing that a large proportion of patients starting dialysis already suffers from cardiac abnormalities and dysfunction and that survival of these patients after a myocardial infarction (MI) was dismal. [33][34][35] In 2003, a statement from several councils from the American Heart Association (AHA) was published in Hypertension and Circulation underscoring the problem of increased cardiovascular risk in CKD, and the lack of knowledge on pathophysiology.…”

Vitamin D3 and cardiovascular function in rats.

“…No statistically significant differences were observed between the two groups of vitamin D3-deficient groups. (26,27). Administration of either 25(OH)D3 (28) or l-a-hydroxyvitamin D3 (27) (34).…”

Analysis of Left-Ventricular Changes Associated with Chronic Hemodialysis

“…In patients with ESRD a chronically elevated cardiac work load due to hyperhydration, hypertension and anemia is frequent [1,3,7,10,12,16,20,21,23,32]. Numerous studies define the morphologic and func tional cardiac status in ESRD [2,7,18,22,31], however, small selected or large unselected groups of ESRD pa tients make it difficult to attribute pathological findings to hemodialysis and distinguish the influence due to preceding or additional influences.…”

“…Numerous studies define the morphologic and func tional cardiac status in ESRD [2,7,18,22,31], however, small selected or large unselected groups of ESRD pa tients make it difficult to attribute pathological findings to hemodialysis and distinguish the influence due to preceding or additional influences. Conflicting results can mainly be attributed to differing selection of patients, study design and choice of methods.…”