Congruence of genomic and ethnolinguistic affinities among five tribal populations of Madhya Pradesh (India)

Mukherjee, N.; Mitra, Mitashree; Chakraborty, Madan; Majumder, Partha P.

doi:10.1007/bf02728944

Cited by 25 publications

(26 citation statements)

References 12 publications

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“…The allele frequency distribution pattern of the populations studied in this paper is quite similar to those observed in other Indian populations (Majumder et al, 1999;Mukherjee et al, 2000;Veerraju et al, 2001;Vishwanathan et al, 2003;Saraswathy et al, 2008). The relatively higher heterozygosity (0.21-0.5) and G ST (4.9%) values reflect the genetic heterogeneity in the studied populations.…”

Section: Discussionsupporting

confidence: 83%

“…The relatively higher heterozygosity (0.21-0.5) and G ST (4.9%) values reflect the genetic heterogeneity in the studied populations. Earlier studies have reported G ST values ranging from as low as 2.5% (Mukherjee et al, 2000) among Madhya Pradesh populations to as high as 8.3% among Southern Indian populations (Vishwanathan et al, 2003).…”

Section: Discussionmentioning

confidence: 92%

“…The neighbour joining tree was constructed based on the DA matrix (Saitou and Nei, 1987). In order to determine the population clustering of the populations studied, principal coordinate analysis was carried out using available data on world populations (Stoneking et al, 1997;Majumder et al, 1999;Mukherjee et al, 2000;Nasidze et al, 2001;Antunez-de-Mayolo et al, 2002;Vishwanathan et al, 2003;Comas et al, 2004;Saraswathy et al, 2008).…”

Section: Discussionmentioning

confidence: 99%

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Genetic sketch of the six population groups of Rajasthan: a study based on 12 autosomal loci

Dada

Saraswathy

Meitei

et al. 2011

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Rajasthan lies on the northwest border of India, and has acted as a major route for human movements since prehistoric and historic times. The present study was conducted to gain an insight into inter-and intrapopulation affinities or variations among the six population groups of Rajasthan. DNA samples from 221 unrelated individuals belonging to six endogamous population groups of Rajasthan, including both tribal (Bhil, Damaria, Garasia, Mina and Saharia) and caste populations (Rajput) were screened for 12 DNA (seven Alu indel and five RFLP) markers. All the loci were found to be polymorphic in all the studied populations. The G ST values which determine the genetic differentiation between the population ranges from 1.5% in LPL to 8.7% in APO. This study suggests that the population groups of Rajasthan are genetically close to other Indian populations, reflecting a common genetic unity among the Indian populations. The study also indicates European gene flow into the populations studied in this paper.

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Section: Discussionsupporting

confidence: 83%

Section: Discussionmentioning

confidence: 92%

Section: Discussionmentioning

confidence: 99%

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Genetic sketch of the six population groups of Rajasthan: a study based on 12 autosomal loci

Dada

Saraswathy

Meitei

et al. 2011

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“…This will also point genetic difference in certain ethnic group. [12,13] Pain abdomen is one of the most common complaint as reported by various studies was also the common complaint in our study. [14,15] Hepatomegaly and spleenomegaly as abdominal sign was comparable to other study.…”

Section: Discussionsupporting

confidence: 62%

Various Surgical Presentations and Their Outcome in Sickle Cell Disease: A Prospective Study

Singh¹,

Chandrakar²,

Agrawal³

et al. 2015

jemds

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ABSTRACT:Sickle cell disease is a common genetic disorder which represents major medical problem in certain parts of world. In India Chhattisgarh is one of the states in which sickle cell disease is common. Purpose of this study was to evaluate the patients of sickle cell disease with various surgical problems and their outcome. A prospective study of 100 patients with diagnosed sickle cell disease was done in the department of General Surgery of Pt. JNM medical college and attached hospital. Maximum patients with surgical presentation were above 40 yrs. of age (48%) with male preponderance. Most common presenting symptom were generalized weakness and abdominal pain (69%). Important clinical sign was pallor 85%, splenomegaly 12%, vasoocclusive crisis in 53%, hemolytic crisis in 4% sequestration crisis in 5% and aplastic crisis seen in 1%. Various surgical presentations were acute appendicitis 14% cholelithiasis 15%, hollow viscous perforation 13% and various other presentations. 63 patients underwent surgical treatment and 37 were managed conservatively. Post operatively delayed wound healing was the common complication 52% due to wound infection 51%. Mortality was 5%. Although causes are multifactorial but patients of sickle cell disease are more prone to develop intra and post-operative complications so it is important for a surgeon to understand the pathophysiology and management of sickle cell disease to reduce the morbidity and mortality of these patients with surgical presentations.

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“…edu/*swatkins/pub/RSP_links.html). The protocols for DRD2 and b-globin markers at the gene are as mentioned by Jorde et al (1995), Kidd et al (1998), Majumdar et al (1999a), and Mukherjee et al (2000). All the restriction site polymorphism markers were digested using 5 U of the appropriate restriction enzyme.…”

Section: Laboratory Analysismentioning

confidence: 99%

A Genomic Insight into Diversity Among Tribal and Nontribal Population Groups of Manipur, India

et al. 2009

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Twenty autosomal markers, including linked markers at two gene markers, are used to understand the genomic similarity and diversity among three tribal (Paite, Thadou, and Kom) and one nontribal communities of Manipur (Northeast India). Two of the markers (CD4 and HB9) are monomorphic in Paite and one (the CD4 marker) in Kom. Data suggest the Meitei (nontribal groups) stand apart from the three tribal groups with respect to higher heterozygosity (0.366) and presence of the highest ancestor haplotypes of DRD2 markers (0.228); this is also supported by principal co-ordinate analysis. These populations are found to be genomically closer to the Chinese population than to other Indian populations.

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Congruence of genomic and ethnolinguistic affinities among five tribal populations of Madhya Pradesh (India)

Cited by 25 publications

References 12 publications

Genetic sketch of the six population groups of Rajasthan: a study based on 12 autosomal loci

Genetic sketch of the six population groups of Rajasthan: a study based on 12 autosomal loci

Various Surgical Presentations and Their Outcome in Sickle Cell Disease: A Prospective Study

A Genomic Insight into Diversity Among Tribal and Nontribal Population Groups of Manipur, India

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