Abstract. We study divisibility properties of certain sums and alternating sums involving binomial coefficients and powers of integers. For example, we prove that for all positive integers n 1 , . . . , n m , n m+1 = n 1 , and any nonnegative integer r, there holdsand conjecture that for any nonnegative integer r and positive integer s such that r + s is odd,where ε = ±1.