Bioactive compounds are nutrients that exert bioactivity in human metabolism, are foods in smaller amounts in the body and have biological properties different from nutritional functions. Currently, several studies have been carried out in order to identify the components responsible for the beneficial properties of foods used in folk and traditional medicine. Thus, the objective of this work was to carry out a narrative review on some of the compounds that have been considered bioactive in foods, evaluating their protective action; presence of organosulfur in Allium sp., fibers, mono and polyunsaturated fatty acids. A search was carried out on the PUBMED, SciELO and Google Scholar platforms considering national and international works published from 2001 to 2021. It was observed that bioactive compounds play an important role in the prevention and treatment of cardiovascular and degenerative diseases such as cancer, diabetes and premature aging. This way, the importance of a diet rich in varieties of fruits and vegetables is highlighted, so that the food is able to offer bioactive compounds in concentrations that are beneficial to the body