Conjugated linoleic acid supplements preserve muscle in high-body-fat adults: A double-blind, randomized, placebo trial

Olive Pomace Oil versus High Oleic Sunflower Oil and Sunflower Oil: A Comparative Study in Healthy and Cardiovascular Risk Humans

“…In relation to SO, previous clinical studies have described that dyslipidemic subjects who substituted their usual oil with SO or canola oil (also rich in PUFA), maintaining their dietary habits, showed no significant changes in weight, BMI, waist circumference and hip circumference after the SO intervention [ 55 ]. When SO was consumed as a dietary supplement (3.2 g/d), any statistically significant change in weight, body fat, waist circumference and BMI was observed, although there was a downward trend [ 56 ]. The present results match with these studies, as there were no statistical changes in the anthropometric parameters measured, except for the decrease in waist circumference ( p = 0.026; Table 4 ), which may be attributed to the higher amount of SO consumed (45 g/d) compared to the latter study 3.2 g/d [ 56 ], and likely to the former [ 52 ] where the quantity of SO oil consumed was ad libitum.…”

“…When SO was consumed as a dietary supplement (3.2 g/d), any statistically significant change in weight, body fat, waist circumference and BMI was observed, although there was a downward trend [ 56 ]. The present results match with these studies, as there were no statistical changes in the anthropometric parameters measured, except for the decrease in waist circumference ( p = 0.026; Table 4 ), which may be attributed to the higher amount of SO consumed (45 g/d) compared to the latter study 3.2 g/d [ 56 ], and likely to the former [ 52 ] where the quantity of SO oil consumed was ad libitum.…”

The effects of conjugated linoleic acid supplementation on lipid profile in adults: A systematic review and dose–response meta-analysis

“…In total, 73 effect sizes were extracted from 56 RCTs, including a total of 3,262 participants (1,773 participants in the CLA group and 1,738 ones in the placebo group). These RCTs were published between 2000 and 2020, from Asia ( n = 18) ( 21 , 27 , 31 , 32 , 59 – 61 , 63 – 66 , 69 , 72 , 76 , 79 , 80 , 82 , 83 ), Europe ( n = 26) ( 30 , 35 , 36 , 38 – 42 , 44 – 47 , 49 – 52 , 54 – 56 , 62 , 67 , 68 , 74 , 75 , 78 , 89 ), America ( n = 10) ( 37 , 43 , 48 , 57 , 70 , 71 , 73 , 77 , 81 , 84 ), Africa ( n = 1) ( 58 ), and Oceania ( n = 1) ( 53 ). All RCTs enrolled both genders except 13 studies that were conducted exclusively on male ( 39 , 41 , 46 , 48 , 49 , 59 , 62 , 73 – 75 , 79 , 81 , 82 ) and 7 studies were performed on female ( 27 , 37 , 63 , 64 , 71 , 77 , ...…”

“…Conjugated linoleic acid (CLA) is a collective term that refers to a heterogeneous group of geometric isomers of linoleic acid; up to 28 isomer forms are detected, of them “c9,t11” and “t10,c12” are especially important ( 20 ). CLA is naturally found in the fat, milk, and meat of ruminant animals such as cow, sheep, and goat ( 20 , 21 ). Accumulating studies have shown the effects of CLA on the management of lipid abnormalities related to CVD and T2DM ( 22 ).…”

The effects of conjugated linoleic acid supplementation on anthropometrics and body composition indices in adults: a systematic review and dose–response meta-analysis

“…Apart from lifestyle modification, often considered the cornerstone of a weight management programme (4)(5)(6) , a wide range of supplements are now available touting anti-obesity properties (7)(8)(9)(10) . Among those, conjugated linoleic acid (CLA) has shown promise as a food supplement to reduce adiposity in preventing overweightness and obesity (11,12) .…”