Conjunctival Myiais caused by Oestrus ovis in a medical college student which responded to Ivermectin

Kumar, Manish; Joseph, Noyal Mariya; Srikanth, K.; Spellman, Stephen R.

doi:10.4103/1755-6783.121027

Cited by 3 publications

(6 citation statements)

References 3 publications

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“…The larvae enter the eye in an outdoor environment; hence men are more likely to be affected. Demographically speaking, most cases in India have been recorded from the southern states, with sporadic, isolated cases reported from other parts of the country and worldwide [8][9][10][11][12][13][14][15][16][17][18][19]. To our knowledge, this is the first series of three cases occurring in close succession in an urban residential area of Punjab.…”

Section: Discussionmentioning

confidence: 99%

External ophthalmomyiasis due to oestrous ovis — a rare case series

Singh¹,

Rajwadkar

Aggarwal³

2022

Ophthalmol J

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Ophthalmomyiasis is an uncommon clinical entity in ophthalmic practice. We report a case series of three patients with external ophthalmomyiasis who presented to a secondary care centre in Pathankot, Punjab, with a history of sudden onset and severe foreign body sensation in the eye. On evaluation, all patients were found to have multiple larvae in the conjunctival sac. They were managed with careful extraction of larvae followed by topical medication. Microbiological analysis identified them as larvae of Oestrous ovis fly in all cases. External ophthalmomyiasis is an uncommon and possibly under-reported entity in North India that requires early diagnosis and treatment.

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Section: Discussionmentioning

confidence: 99%

External ophthalmomyiasis due to oestrous ovis — a rare case series

Singh¹,

Rajwadkar

Aggarwal³

2022

Ophthalmol J

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“…Recently, a new ophthalmic preparation containing 0.6% PVI has been shown to be bactericidal against several Gram-positive and Gram-negative isolates [ 18 ]. Furthermore, 0.6% PVI has also been found to be effective against Demodex mites [ 8 ], a parasite colonizing the eyelid margins, thus offering new prospects for a possible use against other parasites, such as Diptera larvae.…”

Section: Discussionmentioning

confidence: 99%

“…There is already at least one paper indicating efficacy of oral ivermectin (12 mg in a single dose) in treating human conjunctival myiasis caused by O . ovis larvae [ 8 ]. However, the use of systemic ivermectin for the management of ocular surface myiasis is rather questionable, as a topical approach with ointment and/or eye-drops would be much more appropriate.…”

Section: Discussionmentioning

confidence: 99%

“…Oral ivermectin has also been successfully used in the treatment of one case of human conjunctival myiasis caused by O . ovis [ 8 ]. Furthermore, 0.6% povidone-iodine (PVP-I), an iodinated polyvinyl polymer, has recently been found to be effective against Demodex mites , a parasite colonizing the eyelid margins [ 9 ], thus offering new prospects for a possible use against other parasites, such as Diptera larvae.…”

Section: Introductionmentioning

confidence: 99%

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In vitro larvicidal activity of ivermectin and povidone-iodine against Oestrus ovis

et al. 2021

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Purpose To assess the in vitro larvicidal activity of ivermectin and povidone-iodine (PVP-I) against Oestrus ovis, the most frequent cause of external ophthalmomyiasis. Methods L1 O. ovis larvae were collected from the nasal boots of sheep slaughtered in local abattoirs and transferred onto Petri dishes containing mucosal tissue (25 larvae/dish). The larvicidal activity of the following formulations was tested: 1% ivermectin suspension in balanced sterile saline solution (BSSS), 1% ivermectin solution in propylene glycol, propylene glycol, 0.6% PVP-I in hyaluronic acid vehicle (IODIM®), and combination of ivermectin 1% solution and 0.6% PVP-I. One mL of each formulation was added to different Petri dishes containing the larvae. The time needed to kill the larvae was recorded. Results 893 larvae were tested. The median time needed to kill the larvae was 46, 44, 11, 6, and 10 minutes for Iodim®, ivermectin 1% suspension, propylene glycol, ivermectin 1% solution, and a combination of ivermectin 1% solution with 0.6% PVP-I, respectively. Kaplan-Meyer analysis disclosed that the survival curves were significantly lower in samples treated with ivermectin 1% solution, ivermectin 1% solution + 0.6% PVP-I, and propylene glycol than in samples receiving other treatments or BSSS. Conclusion In this in vitro study, ivermectin 1% solution in propylene glycol, ivermectin 1% solution + 0.6% PVP-I, and propylene glycol alone showed a good, relatively rapid larvicidal activity against O. ovis larvae. Further experimental and clinical studies are necessary to establish whether, or not, these formulations may be considered as potential candidates for the topical treatment for external ophthalmomyiasis caused by O. ovis.

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“…Conjunctivitis may be imitated by these initial signs and symptoms of external ophthalmomyiasis. Symptoms have been reported in patients with internal ophthalmomyiasis, including photopsies, floaters, vision lines, and eye pain [5] . Management of infection with ophthalmomyiasis externa can be mainly accomplished by the mechanical removal of larvae from the eye at first and then the patient must be given topical analgesics and antibiotics, larvae attachment to eye tissue by their hooks make the removal difficult because the larvae escape from the edge of the eye to inside when direct slit lamp [6] , using of antihelminthic are less common, in addition to only one case has treated with ivermectin successfully is recorded which" has shown benefit as a therapy and a prophylactic treatment for bot fly infestation of livestock" [2] .…”

Section: Introductionmentioning

confidence: 99%

Study the Effect of Many Medications in Ophthalmomyiasis Treatment and the Possibility of Using these Medications Instead of Mechanical Removal

Jabir¹,

Alomashi²

2021

Indian Journal of Forensic Medicine & Toxicology

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This study was aimed to find the most suitable method to treat ophthalmomyiasis cases in Iraq, especially in diwanyia city. So that the study was conducted on 30 cases, where the drug xylocaine was dropped to the eye eight of them, and turpentine oil was dropped to eight others, while both anesthetics were applied to four of the patients, Then wait for 20 minutes and remove the larvae using forceps and by a specialist ophthalmologist .ten of patients were given ivermectin orally without any ivermectin to gather can immobilize the larvae thus facilitate their removal, it also found that using ivermectin is very effective in the treatment and can be used for clearing eye from larvae even after mechanical removal without any danger from side effect.

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Conjunctival Myiais caused by Oestrus ovis in a medical college student which responded to Ivermectin

Cited by 3 publications

References 3 publications

External ophthalmomyiasis due to oestrous ovis — a rare case series

External ophthalmomyiasis due to oestrous ovis — a rare case series

In vitro larvicidal activity of ivermectin and povidone-iodine against Oestrus ovis

Study the Effect of Many Medications in Ophthalmomyiasis Treatment and the Possibility of Using these Medications Instead of Mechanical Removal

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