Conjunctival myxoma masquerading as conjunctival lymphoma: A case report

Alkharashi, Majed; Alkatan, Hind M.; Alhumidi, Ahmed; Otaif, Wael

doi:10.1016/j.ijscr.2022.107441

Cited by 2 publications

(3 citation statements)

References 12 publications

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“…No gender preference was found in previous studies, [ 9 , 16 , 17 ] however, in a recent review, male individuals were more frequently affected than female individuals (ratio 6:4). [ 13 ] Conjunctival myxomas usually are not associated with a history of trauma or surgery, as in our patient. However, some patients have reported histories of foreign body injuries in the affected eye and prior surgery at the lesional sites, including cataract, [ 18 ] strabismus, [ 19 ] and epiblepharon [ 16 ] surgery.…”

Section: Discussionmentioning

confidence: 58%

“…[ 7 , 9 ] Typically, myxomas present as slow-growing, painless, fleshy gelatinous masses, and appear to be pink or yellow in color. [ 13 ] If such a lesion is present, a myxoma should be considered in the differential diagnosis, and along with surgical excision, histopathological analysis must be performed to establish an accurate diagnosis.…”

Section: Introductionmentioning

confidence: 99%

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Conjunctival myxoma: A case report and review of a rare tumor

Lee,

Kim

et al. 2024

Medicine

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Rationale: Conjunctival myxoma is a rare benign tumor, which can mimic more common conjunctival lesions such as a cyst, lymphangioma, amelanotic nevus, neurofibroma, amelanotic melanoma, or lipoma. We describe a patient with the conjunctival myxoma, who was initially misdiagnosed as a conjunctival cyst. This case report includes intraoperative photographs and various immunohistochemical staining images. Patients concerns: A 55-year-old woman presented with a painless mass in the superotemporal conjunctiva of the left eye, which she had noticed 1 month ago. The patient had no previous history of trauma or eye surgery. Slit-lamp examination revealed a well-circumscribed, freely movable, pinkish, semi-translucent mass on the temporal bulbar conjunctiva, suggestive of a conjunctival cyst. Diagnoses: Histopathological analysis showed stellate- and spindle-shaped cells within the loose myxoid stroma, confirming a diagnosis of conjunctival myxoma. Interventions: The conjunctival lesion was completely excised under local anesthesia. Outcomes: After 4 months of follow-up, the patient remained in good health without recurrence of the conjunctival lesion and no evidence of any systemic abnormality. Lessons: Myxoma is an extremely uncommon benign tumor derived from primitive mesenchyme. Considering the rarity of the tumor and its similarity to other conjunctival tumors, diagnosis can be challenging. Ophthalmologists should consider myxoma as a possible differential diagnosis when encountering conjunctival lesions. Surgical excision is essential to confirm the diagnosis and careful systemic evaluation is required to prevent potentially life-threatening underlying systemic conditions.

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Section: Discussionmentioning

confidence: 58%

Section: Introductionmentioning

confidence: 99%

Conjunctival myxoma: A case report and review of a rare tumor

Lee,

Kim

et al. 2024

Medicine

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“…Famous sites of the neoplastic origin are the atrium of the heart as cardiac myxoma 1,2 and also the jaw bone as gnathic myxoma. In the field of the face and head, myxoma has been rarely detected in the orbit, [3][4][5][6][7][8][9][10][11][12][13][14][15][16][17][18][19][20][21][22] cornea, 23 and conjunctiva [24][25][26][27] of the ocular surface, eyelid, [28][29][30] nasal cavity, and paranasal sinuses. [31][32][33][34][35][36][37][38][39][40] We experienced a patient with orbital myxoma who showed connection with the ethmoid sinus lesion in the follow-up period of 20 years before and after surgical resection of the orbital lesions.…”

Section: Introductionmentioning

confidence: 99%

Resection of Orbital Myxoma With Magnetic Resonance Imaging Evidence of Ethmoid Sinus Origin: Case Report and Review of 20 Patients in the Literature

Matsuo,

Tanaka

2023

Journal of Investigative Medicine High Impact Case Reports

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A 41-year-old woman showed a palpable mass at the superonasal orbital edge on the right side. Magnetic resonance imaging demonstrated a lobulated fluid-containing tubular mass which extended anteriorly to posteriorly along the medial orbital wall, nasal to the eyeball. She was followed once a year for 8 years until the age of 49 years when she decided to undergo surgical resection because of the enlarged mass. The lobulated large mass was resected and the pathology showed sparsely distributed spindle cells, positive for CD34, in alcian blue-positive mucous substances, indicative of myxoma. Postoperative magnetic resonance imaging showed residual lobulated tubular mass along the optic nerve on the medial side and superior to the eyeball. The residual orbital mass showed stable structure with more evident connection with the ethmoid sinus lesion, suggestive of the ethmoid origin, in 12 years until the age of 61 years. In the review of 20 patients with orbital myxomas in the literature, in addition to this case, roughly classified locations in the orbit were retrobulbar in 8 patients, on the lateral side of the orbit in 4, on the superior side in 6, on the medial side in 1 (this patient), and in the orbit with no specific description in 2. In pathological examinations, immunohistochemistry was not done in 8 patients, done but all negative in 2, and positive in 11 patients: nerve sheath myxoma was diagnosed in 3 patients based on positive S100 staining. Orbital myxoma is rare but considered in differential diagnosis of orbital masses.

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Conjunctival myxoma masquerading as conjunctival lymphoma: A case report

Cited by 2 publications

References 12 publications

Conjunctival myxoma: A case report and review of a rare tumor

Conjunctival myxoma: A case report and review of a rare tumor

Resection of Orbital Myxoma With Magnetic Resonance Imaging Evidence of Ethmoid Sinus Origin: Case Report and Review of 20 Patients in the Literature

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