2022
DOI: 10.1097/iop.0000000000002251
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Conjunctival Perivascular Epithelioid Cell Neoplasm With RBM10-TFE3 Fusion Presenting as Recurrent Subconjunctival Hemorrhage

Abstract: Subconjunctival hemorrhages commonly present to eye care professionals and are frequently regarded as benign self-limited conditions. In selected cases, subconjunctival hemorrhages can be a harbinger of more severe disease. Perivascular epithelioid cell tumors, or PEComas, are rare mesenchymal neoplasms believed to originate from perivascular myoid cells and are rarely present in ocular structures. We present a rare case of a conjunctival perivascular epithelioid cell tumor that initially presented with recurr… Show more

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“…Since its original description, a total of ~50 cases of TFE3 -rearranged PEComa have been reported in the literature, mostly as isolated case reports or small series 10,13,15,16,23–51 . A systematic review of the published literature, examining the validity of originally reported associations and potentially identifying new ones, has not been performed.…”
mentioning
confidence: 99%
“…Since its original description, a total of ~50 cases of TFE3 -rearranged PEComa have been reported in the literature, mostly as isolated case reports or small series 10,13,15,16,23–51 . A systematic review of the published literature, examining the validity of originally reported associations and potentially identifying new ones, has not been performed.…”
mentioning
confidence: 99%