Conjunctivitis Due to the Human Adenovirus Type 2 Variant Identified during Epidemic Keratoconjunctivitis Surveillance in Japan

Kaneko, Hisatoshi; Hanaoka, Nozomu; Konagaya, Masami; Tsukahara-Kawamura, Tomoko; Kobayashi, Mariko; Nakagawa, Hayate; Hatano, Hiroshi; Ikuta, Kazufumi; Fujimoto, Tsuguto

doi:10.7883/yoken.jjid.2019.064

Cited by 3 publications

(2 citation statements)

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“…This is probably explained by the ease of spread of Adenoviruses. These viruses can be transmitted from human to human either by direct contact or through contaminated objects [13,14].…”

Section: Discussionmentioning

confidence: 99%

Clinical and Therapeutic Aspects of Viral Ocular Pathology in Brazzaville

2020

JOCR

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Introduction: Viruses can act in two ways, either by a direct pathogenic effect, or indirectly by inducing immunosuppression and favoring the action of other so-called opportunistic viruses. This survey had a double objective, describe the clinical aspects of viral ocular pathology and state its principles of treatment. Materials and Methods: Descriptive cross-sectional study carried out over 2 years at the Ophthalmology department of the University Hospital of Brazzaville. Patients 18 years of age or older with viral ocular pathology were included. The diagnosis was made on the sole basis of anamnestic and / or clinical arguments. None of the viruses involved had been directly detected, with the exception of HIV. Biologically proven patients with a coinfection (bacteria, parasite, fungus) were excluded. HIV serology had been systematic. Four parameters were analyzed: type of virus, structures affected, pathologies diagnosed, anti viral treatments used. Results: Two hundred twenty-five (225) patients were included. The mean age was 44 ± 2.1 years. Sex ratio was 0.8. Viruses: Adenovirus (51.1%), Herpes zoster (19.5%), HIV (18.7%), Herpes simplex (7.5%), CMV (3.2%). Main structures affected: eyelid (86.2%), chorioretin (6.4%). Main pathologies: Adenovirus conjunctivitis (61.1%), shingles (16%), primary herpes simplex infection (8%) Keratitis (6.4%), chorioretinitis (6.4%), uveitis (2.1%). Anti viral treatments used: Valaciclovir, Ganciclovir and anti retroviral. Conclusion: Viral ocular pathology is dominated by Adenovirus conjunctivitis and infections due to 3 types of herpes viridae (Herpes zoster, Herpes simplex and CMV). These herpes viridae are generally responsible for opportunistic diseases following immunosuppression linked to HIV.

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“…This is probably explained by the ease of spread of Adenoviruses. These viruses can be transmitted from human to human either by direct contact or through contaminated objects [13,14].…”

Section: Discussionmentioning

confidence: 99%

Clinical and Therapeutic Aspects of Viral Ocular Pathology in Brazzaville

2020

JOCR

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show abstract

“…Symptomatic treatment with anti-inflammatory eye drops is sufficient to relieve the patient [13][14][15]. Valaciclovir and Ganciclovir have been used, according to the literature, for the treatment of diseases caused by Herpes viridae [14][15][16]. HIV-infected patients have all been treated with anti-retrovirals as recommended by UNAIDS (seen on January 21, 2020 : https://www.unaids.org/en).…”

Section: Discussionmentioning

confidence: 99%